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CCR3 (NM_001837) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC210337L2V
- LentiORF®
-
Lenti ORF particles, CCR3 (mGFP-tagged) - Human chemokine (C-C motif) receptor 3 (CCR3), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | CCR3 (NM_001837) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CC-CKR-3; C C CKR3; CD193; CKR 3; CKR3; CMKBR3 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_001837 |
| ORF Size | 1065 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC210337).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001837.2 |
| RefSeq Size | 1796 bp |
| RefSeq ORF | 1068 bp |
| Locus ID | 1232 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| MW | 41 kDa |
| Gene Summary | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009] |
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