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CLPS (NM_001832) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC205004L3V
- LentiORF®
-
Lenti ORF particles, CLPS (Myc-DDK tagged) - Human colipase, pancreatic (CLPS), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | CLPS (NM_001832) Human Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001832 |
| ORF Size | 336 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC205004).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001832.2 |
| RefSeq Size | 578 bp |
| RefSeq ORF | 339 bp |
| Locus ID | 1208 |
| Protein Families | Secreted Protein, Transmembrane |
| MW | 12 kDa |
| Gene Summary | The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
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