BAG3 (NM_004281) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202860L2V

  • LentiORF®

Lenti ORF particles, BAG3 (mGFP-tagged) - Human BCL2-associated athanogene 3 (BAG3), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,975.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name BAG3 (NM_004281) Human Tagged ORF Clone Lentiviral Particle
Synonyms BAG-3; BIS; CAIR-1; MFM6
Vector pLenti-C-mGFP
ACCN NM_004281
ORF Size 1725 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC202860).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_004281.3
RefSeq Size 2608 bp
RefSeq ORF 1728 bp
Locus ID 9531
Domains WW, BAG
Protein Families Druggable Genome
MW 61.4 kDa
Gene Summary BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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