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Sirt1 (NM_001159589) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR227266L4V
- LentiORF®
-
Lenti ORF particles, Sirt1 (GFP-tagged) - Mouse sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) (Sirt1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 13,110.00
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Specifications
| Product Data | |
| Product Name | Sirt1 (NM_001159589) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA673258; S; Si; Sir2; Sir2a; Sir2alpha; SIR2L1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001159589 |
| ORF Size | 2094 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR227266).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001159589.1 |
| RefSeq Size | 3806 bp |
| RefSeq ORF | 2097 bp |
| Locus ID | 93759 |
| Gene Summary | This gene encodes a member of the sirtuin family of proteins, characterized by their deacetylase activity and proposed role in longevity. The encoded protein regulates gene expression in a wide range of cell and tissue types through its NAD+-dependent deacetylation of histones, transcription factors and transcriptional coactivators. Brain-specific overexpression of this gene has been shown to result in increased median lifespan. Viability of homozygous knockout mice for this gene varies with strain background. Homozygous knockout mice of strains that do not exhibit embryonic lethality are sterile and have a reduced lifespan. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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