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C3 (NM_009778) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226388L3V
- LentiORF®
-
Lenti ORF particles, C3 (Myc-DDK-tagged) - Mouse complement component 3 (C3), 200ul, >10^7 TU/mL
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CNY 22,800.00
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| Product Data | |
| Product Name | C3 (NM_009778) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AI255234; ASP; HSE-MSF; Plp |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_009778 |
| ORF Size | 4989 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226388).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009778.2 |
| RefSeq Size | 5147 bp |
| RefSeq ORF | 4992 bp |
| Locus ID | 12266 |
| Gene Summary | This gene encodes complement protein C3 which plays a central role in the classical, alternative and lectin activation pathways of the complement system. The encoded preproprotein undergoes a multi-step processing to generate various functional peptides. Mice deficient in the encoded protein fail to clear bacteria from the blood stream upon infection, display diminished airway hyperresponsiveness and lung eosinophilia upon allergen-induced pulmonary allergy, and develop severe lung injury after deposition of IgG immune complexes. Deficiency of the homolog of the encoded protein in humans was found to be associated with increased susceptibility to infections, age-related macular degeneration, and atypical hemolytic uremic syndrome. [provided by RefSeq, Mar 2015] |
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