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Masp1 (NM_008555) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226378L3V
- LentiORF®
-
Lenti ORF particles, Masp1 (Myc-DDK-tagged) - Mouse mannan-binding lectin serine peptidase 1 (Masp1), 200ul, >10^7 TU/mL
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CNY 11,875.00
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Specifications
| Product Data | |
| Product Name | Masp1 (NM_008555) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AW048060; CCPII; Crarf; Masp1/3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_008555 |
| ORF Size | 2112 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226378).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008555.2 |
| RefSeq Size | 2752 bp |
| RefSeq ORF | 2115 bp |
| Locus ID | 17174 |
| Gene Summary | Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5. Also plays a role in development.[UniProtKB/Swiss-Prot Function] |
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