Rassf5 (NM_018750) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR222330L4V
- LentiORF®
Lenti ORF particles, Rassf5 (GFP-tagged) - Mouse Ras association (RalGDS/AF-6) domain family member 5 (Rassf5), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Rassf5 (NM_018750) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1300019G20Rik; Maxp1; Nore1; Nore1A; Nore1B; Rapl |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_018750 |
ORF Size | 1242 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222330).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_018750.3, NP_061220.2 |
RefSeq Size | 3421 bp |
RefSeq ORF | 1242 bp |
Locus ID | 54354 |
Gene Summary | Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing (By similarity). May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.[UniProtKB/Swiss-Prot Function] |
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