United States
Germany
Japan
United Kingdom
China
Scin (NM_001146196) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR210229L4V
- LentiORF®
-
Lenti ORF particles, Scin (GFP-tagged) - Mouse scinderin (Scin), transcript variant 1, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 13,205.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Scin (NM_001146196) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | adseverin; AW545522 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001146196 |
| ORF Size | 2145 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR210229).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001146196.1, NP_001139668.1 |
| RefSeq Size | 3008 bp |
| RefSeq ORF | 2148 bp |
| Locus ID | 20259 |
| Gene Summary | Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane (PubMed:9671468). Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity). In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+) (PubMed:9671468). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity). Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts (PubMed:25275604, PubMed:25681458). Regulates chondrocyte proliferation and differentiation (By similarity). Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
