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Cdc20 (NM_023223) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208003L3V
- LentiORF®
-
Lenti ORF particles, Cdc20 (Myc-DDK-tagged) - Mouse cell division cycle 20 homolog (S. cerevisiae) (Cdc20), 200ul, >10^7 TU/mL
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CNY 9,500.00
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Specifications
| Product Data | |
| Product Name | Cdc20 (NM_023223) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2310042N09Rik; C87100; p55CDC |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_023223 |
| ORF Size | 1500 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208003).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_023223.1, NP_075712.1 |
| RefSeq Size | 1793 bp |
| RefSeq ORF | 1500 bp |
| Locus ID | 107995 |
| Gene Summary | Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.[UniProtKB/Swiss-Prot Function] |
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