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Ppif (NM_134084) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202183L3V
- LentiORF®
-
Lenti ORF particles, Ppif (Myc-DDK-tagged) - Mouse peptidylprolyl isomerase F (cyclophilin F) (Ppif), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Ppif (NM_134084) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AW457192; CyP-D; CyP-F; CypD; PPIase |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_134084 |
| ORF Size | 621 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202183).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_134084.1, NP_598845.1 |
| RefSeq Size | 1560 bp |
| RefSeq ORF | 621 bp |
| Locus ID | 105675 |
| Gene Summary | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.[UniProtKB/Swiss-Prot Function] |
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