OSBP2 (NM_001282739) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	HLM; ORP-4; ORP4; OSBPL1; OSBPL4
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_001282739, the custom clone sequence may differ by one or more nucleotides ATGGGGAAAGCGGCGGCTCCGAGCCGAGGCGGCGGCTGTGGCGGCCGCTCCCGCGGGCTCTCGTCGCTGT TCACGGTTGTCCCCTGCCTGTCGTGCCACACGGCGGCGCCGGGCATGAGCGCTTCCACGTCCGGCTCCGG GCCGGAGCCCAAGCCCCAGCCCCAGCCCGTGCCCGAACCGGAGCGGGGACCGCTGTCAGAACAGGTGTCG GAGGCAGTTTCGGAGGCAGTGCCAAGATCGGAACCTGTGTCCGAGACGACGTCTGAGCCGGAGCCAGGGG CTGGGCAGCCATCGGAACTGCTGCAGGGGTCGCGGCCGGGGTCAGAGTCAAGCTCAGGTGTAGGGGCTGG GCCCTTCACTAAGGCCGCATCGGAGCCGCTCTCCCGGGCGGTGGGGAGCGCGACCTTTCTCAGACCCGAG TCAGGATCGCTGCCAGCGTTAAAGCCCCTGCCTCTTCTGCGACCAGGACAGGCGAAGACTCCTCTTGGGG TTCCAATGTCGGGGACTGGCACGACCTCCAGTGCCCCACTGGCCTTACTGCCTCTGGACAGCTTCGAGGG CTGGCTTCTCAAGTGGACCAACTATCTGAAGGGCTACCAGCGCCGCTGGTTCGTGCTGGGCAATGGTTTG CTCTCTTACTACAGAAATCAGGGTGAAATGGCCCACACGTGCCGTGGAACCATCAACCTGTCCACCGCGC ACATTGACACGGAGGACTCTTGTGGTATCTTGCTGACCAGTGGGGCCAGGAGCTACCACCTCAAGGCCAG CTCAGAGGTGGACCGGCAGCAGTGGATCACCGCCCTGGAGCTGGCCAAGGCCAAGGCTGTCCGCGTGATG AACACTCATTCAGATGACTCTGGGGACGACGACGAGGCTACCACCCCAGCCGACAAGAGCGAGCTGCACC ACACCCTGAAGAATCTTTCCCTGAAGTTAGATGACCTCAGCACGTGCAATGACCTCATCGCCAAGCACGG CGCTGCACTCCAGCGCTCCCTGACAGAGCTGGACGGCCTCAAGATCCCATCTGAGAGTGGGGAGAAGCTG AAGGTGGTGAATGAGCGGGCCACCCTCTTCCGCATCACATCCAATGCTATGATCAACGCCTGCAGGGACT TCTTGGAACTAGCAGAGATACACAGTCGGAAATGGCAGCGGGCACTGCAGTATGAGCAGGAGCAGCGCGT GCACTTGGAGGAAACCATTGAGCAGCTGGCGAAGCAGCACAACAGCCTCGAGCGGGCCTTCCACAGTGCC CCTGGCCGGCCGGCCAACCCCTCCAAGAGCTTCATTGAGGGAAGCCTCTTGACTCCCAAAGGAGAGGACA GTGAGGAAGATGAAGATACCGAGTACTTTGATGCCATGGAAGACTCCACATCCTTCATCACCGTGATCAC CGAGGCCAAGGAAGACAGAAAAGCTGAAGGTAGCACCGGGACAAGTTCCGTGGACTGGAGCTCAGCAGAC AATGTACTAGATGGTGCCTCGCTCGTGCCCAAGGGTTCATCCAAAGTCAAGAGGCGAGTCCGCATTCCCA ACAAGCCCAACTACAGCCTTAACCTCTGGAGCATCATGAAGAACTGCATCGGCCGGGAGCTCTCCAGGAT CCCCATGCCGGTGAACTTCAATGAGCCCCTGTCCATGCTCCAGCGGCTGACAGAGGACCTGGAGTACCAC CACCTGCTGGACAAGGCAGTGCACTGCACCAGCTCAGTGGAGCAGATGTGCCTGGTGGCCGCCTTCTCTG TGTCCTCCTACTCCACCACAGTGCACCGCATCGCCAAGCCCTTCAACCCCATGCTGGGGGAGACCTTCGA GCTGGACCGCCTCGACGACATGGGCCTGCGCTCCCTCTGTGAGCAGGTGAGCCACCACCCCCCCTCAGCT GCGCACTACGTGTTCTCCAAGCATGGCTGGAGCCTCTGGCAGGAGATCACCATCTCCAGCAAGTTCCGGG GAAAATACATCTCCATCATGCCGCTAGGTGCCATCCACTTAGAATTCCAGGCCAGTGGGAATCACTACGT GTGGAGGAAGAGCACCTCAACTGTTCACAACATCATCGTGGGCAAGCTCTGGATCGACCAGTCAGGGGAC ATCGAGATTGTGAACCATAAGACCAATGACCGGTGCCAGCTGAAGTTCCTGCCCTACAGCTACTTCTCCA AAGAGGCAGCCCGGAAGGTGACAGGAGTGGTGAGTGACAGCCAGGGCAAGGCCCATTACGTGCTGTCCGG CTCGTGGGATGAACAAATGGAGTGCTCCAAGGTCATGCATAGCAGTCCCAGCAGCCCCAGCTCTGACGGG AAGCAGAAGACAGTGTACCAGACCCTGTCAGCCAAGCTGCTGTGGAAGAAGTACCCGCTGCCGGAGAACG CGGAGAACATGTACTACTTCTCAGAGCTGGCCCTGACCCTCAACGAGCACGAGGAGGGCGTAGCGCCAAC CGACAGCCGCCTGCGGCCCGACCAGCGGCTGATGGAGAAGGGCCGTTGGGACGAGGCCAATACCGAGAAG CAGCGGCTGGAGGAGAAGCAGCGCCTGTCGCGGCGCCGGCGGCTGGAGGCCTGCGGGCCGGGCAGCAGCT GCAGCTCGGAGGAAGAGAAGGAGGCGGATGCCTACACGCCACTGTGGTTTGAGAAGAGGCTGGATCCGCT GACCGGGGAGATGGCCTGTGTGTACAAGGGCGGCTACTGGGAGGCCAAGGAGAAGCAAGACTGGCATATG TGCCCCAACATCTTCTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001282739
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001282739.1, NP_001269668.1
RefSeq Size	4346 bp
RefSeq ORF	2748 bp
Locus ID	23762
UniProt ID	Q969R2
Gene Summary	The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013] Transcript Variant: This variant (4) uses an alternate in-frame splice site, compared to variant 1. The encoded isoform (d) is shorter than isoform a.

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