UBASH3A (NM_001243467) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CLIP4; STS-2; TULA; TULA-1
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC330124 representing NM_001243467. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCAGCGGGGGAGACGCAGCTCTACGCCAAGGTCTCCAACAAGCTCAAGAGCCGCAGCAGCCCCTCG CTCCTGGAGCCCCTCCTGGCCATGGGCTTCCCGGTGCACACCGCGCTGAAAGCGTTGGCAGCCACGGGG AGGAAGACGGCGGAGGAGGCCTTGGCCTGGCTGCATGATCATTGCAATGACCCTTCCCTAGACGACCCC ATCCCCCAGGAGTATGCCCTTTTCCTCTGTCCAACGGGGCCCCTGCTGGAAAAACTTCAAGAGTTCTGG AGAGAGAGCAAGCGCCAGTGTGCAAAGAACAGAGCTCATGAGGTCTTCCCACACGTGACACTCTGTGAC TTCTTCACGTGTGAAGACCAGAAGGTGGAATGCCTGTACGAGGCGCTGAAGAGAGCTGGAGACAGGCTC CTGGGCTCCTTCCCCACGGCCGTGCCTCTGGCTCTCCACTCCTCCATCAGCTACCTCGGCTTCTTCGTC AGTGGCAGCCCCGCAGACGTCATCCGGGAATTCGCCATGACCTTCGCCACGGAAGCATCTCTCTTAGCA GACTGCTCCGTGAAGCCTTGCACCAAACAGCTGCATCTGACCTTGGCCCACAAGTTCTACCCCCACCAC CAGAGGACGCTGGAGCAGCTGGCCAGAGCCATCCCCCTGGGCCACAGCTGCCAGTGGACCGCAGCACTC TACTCCCGAGACATGCGCTTTGTGCACTACCAGACCCTGAGAGCCCTATTCCAGTACAAACCCCAGAAC GTGGATGAGCTGACGCTAAGTCCTGGTGACTACATCTTTGTGGACCCCACGCAGCAGGACGAAGCCAGC GAGGGCTGGGTGATTGGGATCTCACAGCGGACGGGCTGCCGGGGCTTCCTGCCGGAAAACTACACGGAT CGAGCCAGTGAGTCTGACACGTGGGTGAAGCACAGGATGTACACCTTCAGTCTAGCCACAGACCTGAAC TCCAGAAAGGATGGTGAAGCCAGCAGCAGATGCAGCGGGGAATTTCTTCCACAAACGGCAAGGAGTCTT AGCAGCTTACAGGCCTTGCAGGCTACCGTTGCAAGGAAGAGCGTGCTGGTGGTTCGCCACGGGGAGAGA GTGGATCAGATCTTCGGGAAGGCATGGCTGCAGCAATGCTCCACTCCTGATGGGAAATACTACAGGCCA GACCTGAATTTCCCCTGCAGTCTGCCAAGACGGAGTCGTGGGATCAAAGACTTTGAAAACGATCCCCCA TTATCATCGTGTGGCATTTTCCAGTCCAGAATTGCAGGGGACGCGCTACTGGACAGTGGTATCAGAATC AGCTCTGTGTTTGCCTCCCCAGCCCTCCGCTGTGTGCAGACGGCCAAACTCATCCTGGAAGAACTCAAA CTGGAGAAAAAAATCAAGATACGAGTGGAACCTGGAATCTTTGAATGGACAAAATGGGAAGCTGGCAAA ACCACCCCAACCCTCATGAGCCTGGAAGAGCTGAAAGAGGCAAATTTCAACATTGACACTGATTACAGA TCCCTTCCCTGGGCATGTGCTTCTGTGAAGAAAATAAAGAGGAAGGAAAATGGGAGTTGGTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001243467
Insert Size	1581 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001243467.1
RefSeq Size	2225 bp
RefSeq ORF	1581 bp
Locus ID	53347
UniProt ID	P57075
Protein Families	Druggable Genome
MW	59.2 kDa
Gene Summary	This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region, and two alternate exons that result in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.

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