United States
Germany
Japan
United Kingdom
China
SMPDL3B (NM_001009568) Human Untagged Clone
CAT＃: SC319522
SMPDL3B (untagged)-Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 2
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ASML3B |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001009568.1
GACGCCTTGGAGGACTTGGAACACCTGTAACAGGACAAGGAGTCCTGCTCCGGCACGTGG
CCACAGAAAACTACTTAGGAAGCCTGTGGTGAGAACAACAACAGTGCCTGGAGAATCCCA CGGCTCTGGGGAAGTGAGCCCCGAGGATGAGGCTGCTCGCCTGGCTGATTTTCCTGGCTA ACTGGGGAGGTGCCAGGGCTGAACCAGGGAAGTTCTGGCACATCGCTGACCTGCACCTTG ACCCTGACTACAAGGTATCCAAAGACCCCTTCCAGGTGTGCCCATCAGCTGGATCCCAGC CAGTGCCCGACGCAGGCCCCTGGGGTGACTACCTCTGTGATTCTCCCTGGGCCCTCATCA ACTCCTCCATCTATGCCATGAAGGAGATTGAGCCAGAGCCAGACTTCATTCTCTGGACTG GTGATGACACGCCTCATGTGCCCGATGAGAAACTGGGAGAGGCAGCTGTACTGGAAATTG TGGAACGCCTGACCAAGCTCATCAGAGAGGTCTTTCCAGATACTAAAGTCTATGCTGCTT TGGGAAATCATGATTTTCACCCCAAAAACCAGTTCCCAGCTGGAAGTAACAACATCTACA ATCAGATAGCAGAACTATGGAAACCCTGGCTTAGTAATGAGTCCATCGCTCTCTTCAAAA AAGGTGCCTTCTACTGTGAGAAGCTGCCGGGTCCCAGCGGGGCTGGGCGAATTGTGGTCC TCAACACCAATCTGTACTATACCAGCAATGCGCTGACAGCAGACATGGCGGACCCTGGCC AGCAGTTCCAGTGGCTGGAAGATGTGCTGACCGATGCATCCAAAGCTGGGGACATGGTGT ACATTGTCGGCCACGTGCCCCCGGGGTTCTTTGAGAAGACGCAAAACAAGGCATGGTTCC GGGAGGGCTTCAATGAAAAATACCTGAAGGTGGTCCGGAAGCATCATCGCGTCATAGCAG GGCAGTTCTTCGGGCACCACCACACCGACAGCTTTCGGATGCTCTATGATGATGCAGGTG TCCCCATAAGCGCCATGTTCATCACACCTGGAGTCACCCCATGGAAAACCACATTACCTG GAGTGGTCAATGGGGCCAACAATCCAGCCATCCGGGTGTTCGAATATGACCGAGCCACAC TGAGCCTGAAGGTCAGGAGTCCTGCGGAGGCCAGAGGAGGAGGGTGGGAGGGGCTTAAAT GCATCACCACCTTCCCTCACTCTCAGCTTATCCACCTTCCCCTGACCACTGAGCCTCAGG AAGGTTGAGCTCCTTCCACCCTTCTCCAGCTCAGGATCAGAACCCTGGAGGCACCTGCCA CCGAGTCAGGGCAGTGCCTCACCAAGTCACCTTTTCCCCTGGATGACTGTCACAGCCTCA TACCTGGTCTCCCTGCCTCTGGCCCTGCCCTGCTATGGCCCATCCGCTACACAAGAGAGA AGAAACTAATCTCCTATAGCACCACTTTCATCTTGTCTCCGTCCTGCTCAAAAACCTTCA GTGGCTCCCCAGTGCCTTCAAGATAAAGTTGTGTCTCCTTGACCTAGTAAAAAAAAAAAA AAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001009568 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001009568.1, NP_001009568.1 |
| RefSeq Size | 1611 bp |
| RefSeq ORF | 1122 bp |
| Locus ID | 27293 |
| UniProt ID | Q92485 |
| Protein Families | Secreted Protein |
| Gene Summary | Lipid-modulating phosphodiesterase (PubMed:26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown (PubMed:26095358). Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204846 | SMPDL3B (Myc-DDK-tagged)-Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 2 |
CNY 3,656.00 |
|
| RC204846L3 | Lenti ORF clone of Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204846L4 | Lenti ORF clone of Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG204846 | SMPDL3B (tGFP-tagged) - Human sphingomyelin phosphodiesterase, acid-like 3B (SMPDL3B), transcript variant 2 |
CNY 4,370.00 |
其它SMPDL3B产品
