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HERC4 (BC039600) Human Untagged Clone
CAT＃: SC315116
HERC4 (untagged)-Homo sapiens, Similar to hect domain and RLD 3, clone MGC:48902 IMAGE:5212048, complete cds
CNY 27,270.00
货期*
7周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DKFZP564G092 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for BC039600, the custom clone sequence may differ by one or more nucleotides
ATGTTGTGCTGGGGAAATGCATCCTTTGGGCAGCTAGGTTTGGGTGGAATTGATGAAGAA ATTGTACTAGAGCCCAGAAAAAGTGACTTCTTTATAAATAAAAGGGTCCGAGATGTAGGA TGTGGACTCAGACATACTGTGTTTGTTCTGGATGATGGAACAGTGTACACATGTGGATGT AATGATCTAGGACAGCTAGGTCATGAAAAATCCAGAAAGAAACCAGAGCAGGTTGTTGCC CTGGATGCCCAAAATATTGTAGCTGTTTCATGTGGAGAAGCTCATACGTTAGCGCTAAAT GACAAAGGCCAGGTGTATGCTTGGGGTCTCGATTCTGATGGACAGCTTGGCCTGGTAGGA TCAGAGGAATGCATCAGAGTACCCAGAAATATTAAAAGTTTGTCAGATATCCAGATTGTA CAGGTTGCTTGTGGTTACTATCATTCACTTGCACTTTCTAAAGCAAGTGAAGTCTTCTGT TGGGGACAGAATAAATATGGCCAATTGGGTTTAGGTACTGACTGTAAAAAGCAAACTTCA CCGCAGCTGCTTAAGTCTTTGCTTGGAATCCCTTTCATGCAAGTTGCAGCAGGAGGAGCC CATAGTTTTGTACTCACCCTTTCTGGAGCTATCTTTGGATGGGGACGCAACAAGTTTGGT CAGCTAGGTCTTAATGATGAAAATGATAGGTATGTTCCTAATTTACTAAAGTCACTAAGA TCTCAGAAAATAGTTTATATTTGTTGTGGAGAAGATCATACTGCTGCTCTAACCAAGGAA GGTGGAGTGTTTACTTTTGGAGCTGGAGGGTATGGTCAGTTGGGCCATAATTCTACCAGT CATGAAATAAACCCAAGGAAAGTTTTTGAACTTATGGGAAGCATTGTCACTGAGATTGCT TGTGGACGGCAGCACACTTCTGCTTTTGTTCCTTCATCAGGACGAATTTACTCTTTTGGG CTTGGTGGTAATGGGCAGCTGGGAACCGGTTCAACAAGCAACAGGAAAAGCCCCTTTACT GTAAAAGGAAATTGGTACCCCTATAATGGGCAGTGTCTACCAGATATTGATTCTGAAGAA TATTTCTGTGTAAAAAGAATTTTCTCAGGGGGAGATCAAAGCTTTTCACATTACTCTAGT CCCCAGAACTGTGGGCCACCAGATGACTTCAGATGTCCCAATCCGACAAAGCAGATCTGG ACAGTGAATGAAGCTCTAATTCAGAAATGGCTGAGCTATCCTTCTGGAAGGTTTCCTGTG GAGATAGCCAATGAGATAGATGGAACGTTTTCTTCCTCTGGTTGCCTAAATGGAAGTTTT TTAGCTGTTAGCAATGATGATCACTATAGAACAGGTACCAGATTTTCAGGGGTTGATATG AATGCTGCTAGGCTTTTATTCCACAAACTTATACAACCTGATCATCCGCAGATATCTCAG CAGGTGGCAGCTAGTTTGGAAAAGAATCTTATTCCTAAACTGACTAGCTCCTTACCTGAT GTTGAAGCATTGAGGTTTTATCTTACTCTACCAGAATGTCCCCTGATGAGTGATTCCAAC AATTTCACAACAATAGCAATTCCCTTTGGTACAGCTCTTGTGAACCTAGAAAAGGCACCA CTGAAAGTACTTGAAAACTGGTGGTCAGTACTTGAACCTCCACTATTCCTCAAGATAGTA GAACTTTTTAAGGAAGTTGTGGTACATCTTTTGAAACTCTACAAGATCGGTATTCCCCCT TCTGAAAGAAGAATTTTCAACAGTTTTCTTCATACTGCATTAAAGGTTTTAGAAATACTA CATAGGGTAAATGAGAAAATGGGACAGATTATACAGTATGATAAATTTTATATACATGAA GTACAAGAATTGATAGACATAAGAAATGATTATATCAACTGGGTCCAACAGCAGGCCTAT GGAATGTTGGCAGATATCCCTGTTACAATCTGTACATATCCATTTGTATTTGATGCCCAA GCAAAAACTACTCTGTTACAGACCGATGCAGTCTTACAGATGCAGATGGCTATTGATCAG GCCCACAGGCAGAATGTCTCCTCTCTTTTTCTCCCAGTGATTGAATCTGTGAATCCCTGC TTAATTCTAGTGGTGCGTAGAGAAAATATTGTAGGAGATGCAATGGAAGTCCTTAGGAAA ACAAAGAACATAGATTACAAGAAGCCACTCAAGGTTATATTTGTTGGAGAAGATGCTGTG GATGCAGGAGGGGTGCGCAAAGAATTTTTCTTGCTCATCATGAGGGAATTATTGGATCCT AAATACGGCATGTTTAGGTATTATGAAGATTCCAGGCTCATTTGGTTTTCTGATAAGACA TTTGAAGACAGTGATTTGTTCCATTTGATTGGTGTTATCTGTGGCTTAGCAATTTATAAT TGTACCATTGTGGACCTCCATTTTCCTTTGGCTTTATATAAGAAACTACTGAAAAAGAAG CCATCCTTGGATGATTTGAAAGAACTAATGCCTGATGTTGGGAGAAGCATGCAACAGTTA CTGGATTATCCAGAAGATGACATAGAGGAAACATTTTGTCTTAATTTTACGATCACAGTT GAAAACTTTGGTGCAACAGAAGTGAAAGAGCTGGTTCTAAATGGTGCAGACACAGCTGTT AACAAACAAAATCGGCAAGAGTTTGTCGATGCTTATGTGGATTACATATTCAATAAATCA GTGGCTTCCTTATTTGATGCTTTTCATGCGGGCTTTCATAAGGTCTGTGGAGGAAAAGTC CTTCTGCTCTTTCAGCCTAATGAACTACAAGCAATGGTCATTGGAAATACAAATTATGAT TGGAAGGAACTGGAAAAGAATACAGAATACAAAGGGGAATATTGGGCAGAACATCCTACG ATAAAAATTTTTTGGGAAGTATTTCACGAATTACCATTGGAAAAGAAGAAACAGTTTCTG TTATTTTTGACAGGTAGTGATCGCATTCCTATTCTTGGTATGAAGAGTCTGAAACTAGTC ATCCAGTCCACAGGAGGTGGTGAGGAGTATCTCCCAGTTTCCCATACTTGTTTTAATCTT CTGGATCTTCCAAAATATACAGAAAAAGAAACTCTACGCTCTAAACTGATCCAAGCTATT GATCACAATGAAGGCTTCAGTTTAATA |
| Restriction Sites | Please inquire |
| ACCN | BC039600 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC039600.1, AAH39600.1 |
| RefSeq Size | 3842 bp |
| RefSeq ORF | 3150 bp |
| Locus ID | 26091 |
| Protein Families | Druggable Genome |
| Protein Pathways | Ubiquitin mediated proteolysis |
| Gene Summary | HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008] |
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