SORBS2 (AF396457) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AF396457, the custom clone sequence may differ by one or more nucleotides ATGAAAGCAACAACACCTTTGCAGACAGTCGACCGGCCCAAGGACTGGTACAAGACGATG TTTAAGCAAATTCACATGGTGCACAAGCCGGATGATGACACAGACATGTATAATACTCCT ACACCTCACATGAAATATACATACAATGCAGGTCTGTACAACCCACCCTACAGTGCTCAG TCACACCCTGCTGCAAAGACCCAAACCTACAGACCTCTTTCCAAAAGCCACTCCGACAAC AGCCCCAATGCCTTTAAGGATGCGTCCTCCCCAGTGCCTCCCCCACATGTTCCACCTCCA GTCCCGCCGCTTCGACCAAGAGATCGGTCTTCAACAGAAAAGCATGACTGGGATCCTCCA GACAGAAAAGTGGACACAAGAAATTTCGGGTCTGAGCCAAGGAGTATTTTTGAATACGAG GACAGAAAAGTGGACACGAGAAAATTTCGATCGGAGCCACGGTCTATTTTTGAATACGAG CCTGGGAAGTCATCCATCCTGCAGCACGAACGACCCGTCTACCAGTCTTCCATAGACAGA AGCTTGGAAAGACCCAGCAGCTCTGCAAGCATGGCGGGTGACTTTAGAAAACGGAGGAAG AGTGAACCTGCAGTGGGCCCGCCCAGGGGCTTGGGGGATCACAGTTCAAGCAGGACCAGC CCCGGCCGGGCAGACCTCCCAGGATCAAGTTCCACCTTTACCACGTCTTTCATTAGTTCT TCTCCTTCCTCTCCCTCGAGAGCACAAGGTGGGGATGATAGCAAAATGTGTCCGCCCCTT TGCAGTTACTCGGGGCTCAATGGCTCGCCCTCTAGTGAGTTAGAGTGCTGCGGCGCTTAT AGAAGGCACTTGGACGTCCCCCAGGACTCTCAAAGGGCCATCACTTTCAAGAACGGCTGG CAAATGGCCCGGCAAAATGCAGAGATCTGGAGTAGCACTGAAGAGGCGGTTTCCCCCAAA ATCAAATCACGAAGCTGTGACGATCTCCTGAATGATGACTGCGGCAGCTTCCCAGACCCT AAAACCAAGTCAGAAAGCATGGGTTCTCTGTTATGTGACGAAGGCTCCAAAGAGAGCGAC CCCATGACGTGGACTTCCCCCTACATCCCGGAAGTGTGCGGGAACAGCAGAGAATTCATG TTAAGCAAATGGATATTCGTGGAATCTCTGGATGGAGGACCATTTTGGAAAGTGCTAAAG GAATATCTAGAGCGAGTGAGGAATCTA
Restriction Sites	Please inquire
ACCN	AF396457
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AF396457.1, AAK81860.1
RefSeq Size	1569 bp
RefSeq ORF	1569 bp
Locus ID	8470
Domains	Sorb
Gene Summary	Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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