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ROR gamma (RORC) (NM_001001523) Human Untagged Clone
CAT＃: SC300207
RORC (untagged)-Human RAR-related orphan receptor C (RORC), transcript variant 2
CNY 5,488.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IMD42; NR1F3; RORG; RZR-GAMMA; RZRG; TOR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001001523 edited
GTCATGAGAACACAAATTGAAGTGATCCCTTGCAAAATCTGTGGGGACAAGTCGTCTGGG ATCCACTACGGGGTTATCACCTGTGAGGGGTGCAAGGGCTTCTTCCGCCGGAGCCAGCGC TGTAACGCGGCCTACTCCTGCACCCGTCAGCAGAACTGCCCCATCGACCGCACCAGCCGA AACCGATGCCAGCACTGCCGCCTGCAGAAATGCCTGGCGCTGGGCATGTCCCGAGATGCT GTCAAGTTCGGCCGCATGTCCAAGAAGCAGAGGGACAGCCTGCATGCAGAAGTGCAGAAA CAGCTGCAGCAGCGGCAACAGCAGCAACAGGAACCAGTGGTCAAGACCCCTCCAGCAGGG GCCCAAGGAGCAGATACCCTCACCTACACCTTGGGGCTCCCAGACGGGCAGCTGCCCCTG GGCTCCTCGCCTGACCTGCCTGAGGCTTCTGCCTGTCCCCCTGGCCTCCTGAAAGCCTCA GGCTCTGGGCCCTCATATTCCAACAACTTGGCCAAGGCAGGGCTCAATGGGGCCTCATGC CACCTTGAATACAGCCCTGAGCGGGGCAAGGCTGAGGGCAGAGAGAGCTTCTATAGCACA GGCAGCCAGCTGACCCCTGACCGATGTGGACTTCGTTTTGAGGAACACAGGCATCCTGGG CTTGGGGAACTGGGACAGGGCCCAGACAGCTACGGCAGCCCCAGTTTCCGCAGCACACCG GAGGCACCCTATGCCTCCCTGACAGAGATAGAGCACCTGGTGCAGAGCGTCTGCAAGTCC TACAGGGAGACATGCCAGCTGCGGCTGGAGGACCTGCTGCGGCAGCGCTCCAACATCTTC TCCCGGGAGGAAGTGACTGGCTACCAGAGGAAGTCCATGTGGGAGATGTGGGAACGGTGT GCCCACCACCTCACCGAGGCCATTCAGTACGTGGTGGAGTTCGCCAAGAGGCTCTCAGGC TTTATGGAGCTCTGCCAGAATGACCAGATTGTGCTTCTCAAAGCAGGAGCAATGGAAGTG GTGCTGGTTAGGATGTGCCGGGCCTACAATGCTGACAACCGCACGGTCTTTTTTGAAGGC AAATACGGTGGCATGGAGCTGTTCCGAGCCTTGGGCTGCAGCGAGCTCATCAGCTCCATC TTTGACTTCTCCCACTCCCTAAGTGCCTTGCACTTTTCCGAGGATGAGATTGCCCTCTAC ACAGCCCTTGTTCTCATCAATGCCCATCGGCCAGGGCTCCAAGAGAAAAGGAAAGTAGAA CAGCTGCAGTACAATCTGGAGCTGGCCTTTCATCATCATCTCTGCAAGACTCATCGCCAA AGCATCCTGGCAAAGCTGCCACCCAAGGGGAAGCTTCGGAGCCTGTGTAGCCAGCATGTG GAAAGGCTGCAGATCTTCCAGCACCTCCACCCCATCGTGGTCCAAGCCGCTTTCCCTCCA CTCTACAAGGAGCTCTTCAGCACTGAAACCGAGTCACCTGTGGGGCTGTCCAAGTGACCT GGAAGAGGGACTCCTTGCCTCTCCCTATGGCCTGCTGGCCCACCTCCCTGGACCCCGTTC CACCCTCACCCTTTTCCTTTCCCATGAACCCTGGAGGGTGGTCCCCACCAGCTCTTTGGA AGTGAGCAGATGCTGCGGCTGGCTTTCTGTCAGCAGGCCGGCCTGGCAGTGGGACAATCG CCAGAGGGTGGGGCTGGCAGAACACCATCTCCAGCCTCAGCTTTGACCTGTCTCATTTCC CATATTCCTTCACACCCAGCTTCTGGAAGGCATGGGGTGGCTGGGATTTAAGGACTTCTG GGGGACCAAGACATCCTCAAGAAAACAGGGGCATCCAGGGCTCCCTGGATGAATAGAATG CAATTCATTCAGAAGCTCAGAAGCTAAGAATAAGCCTTTGAAATACCTCATTGCATTTCC CTTTGGGCTTCGGCTTGGGGAGATGGATCAAGCTCAGAGACTGGCAGTGAGAGCCCAGAA GGACCTGTATAAAATGAATCTGGAGCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_001001523 unedited
TTGTCCAGGTTAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGG TCATGAGAACACAAATTGAAGTGATCCCTTGCAAAATCTGTGGGGACAAGTCGTCTGGGA TCCACTACGGGGTTATCACCTGTGAGGGGTGCAAGGGCTTCTTCCGCCGGAGCCAGCGCT GTAACGCGGCCTACTCCTGCACCCGTCAGCAGAACTGCCCCATCGACCGCACCAGCCGAA ACCGATGCCAGCACTGCCGCCTGCAGAAATGCCTGGCGCTGGGCATGTCCCGAGATGCTG TCAAGTTCGGCCGCATGTCCAAGAAGCAGAGGGACAGCCTGCATGCAGAAGTGCAGAAAC AGCTGCAGCAGCGGCAACAGCAGCAACAGGAACCAGTGGTCAAGACCCCTCCAGCAGGGG CCCAAGGAGCAGATACCCTCACCTACACCTTGGGGCTCCCAGACGGGCAGCTGCCCCTGG GCTCCTCGCCTGACCCTGCCTGAGCTTCTGCCTGTCCCCCTGGCCTCCTGAAAGCCTCAN GCTCTGGGCCCTCATATTCCAACACTTGGCCAAGGCAGGGCTCAATGGGGCCTCATGCCA CCTTGAATACAGCCCTGAGCGGNGCAAGGCTGAGGGCAGAGAGAGCTTCTATAGCACAGG CAGCCAGCTGACCCCTGACCGATGTGGACTTCGTTTTGAGGAAACACAGCATCCTGGGCT TGGGGAAACTGGACAAGGCCAANCAGCTACGGCAGCCCCAGTTTTCGCAGCACACGGGAA GCACCCTATGCTCCCTGACCGAAATAAAGCACCTGGTGCAAAGCGTCTGCAAGTCCTACG GGGAAACATGCCAACCTGCGCTGGAGAACTGCTTGGGAAACCTTCCACATTTTTCC |
| Restriction Sites | Please inquire |
| ACCN | NM_001001523 |
| Insert Size | 2100 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001001523.1, NP_001001523.1 |
| RefSeq Size | 3054 bp |
| RefSeq ORF | 1494 bp |
| Locus ID | 6097 |
| UniProt ID | P51449 |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter and has a distinct N-terminus compared to isoform a. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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The cardenolides strophanthidin, digoxigenin and dihydroouabain act as activators of the human RORγ/RORγT receptors
,Karaś, K;Sałkowska, A;Walczak-Drzewiecka, A;Ryba, K;Dastych, J;Bachorz, RA;Ratajewski, M;,
Toxicol. Lett.
,PubMed ID 29981919
[RORC]
|
|
Digoxin, an Overlooked Agonist of RORγ/RORγT
,Karaś, K;Sałkowska, A;Sobalska-Kwapis, M;Walczak-Drzewiecka, A;Strapagiel, D;Dastych, J;Bachorz, RA;Ratajewski, M;,
Front Pharmacol
,PubMed ID 30666196
[RORC]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212239 | RORC (Myc-DDK-tagged)-Human RAR-related orphan receptor C (RORC), transcript variant 2 |
CNY 5,488.00 |
|
| RC212239L1 | Lenti ORF clone of Human RAR-related orphan receptor C (RORC), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC212239L2 | Lenti ORF clone of Human RAR-related orphan receptor C (RORC), transcript variant 2, mGFP tagged |
CNY 6,270.00 |
|
| RC212239L3 | Lenti ORF clone of Human RAR-related orphan receptor C (RORC), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC212239L4 | Lenti ORF clone of Human RAR-related orphan receptor C (RORC), transcript variant 2, mGFP tagged |
CNY 7,888.00 |
|
| RG212239 | RORC (tGFP-tagged) - Human RAR-related orphan receptor C (RORC), transcript variant 2 |
CNY 7,088.00 |
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