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RAC2 (NM_002872) Human Untagged Clone
CAT＃: SC118358
RAC2 (untagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2)
CNY 3,600.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EN-7; Gx; HSPC022; IMD73A; IMD73B; IMD73C; p21-Rac2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118358 sequence for NM_002872 edited (data generated by NextGen Sequencing)
ATGCAGGCCATCAAGTGTGTGGTGGTGGGAGATGGGGCCGTGGGCAAGACCTGCCTTCTC ATCAGCTACACCACCAACGCCTTTCCCGGAGAGTACATCCCCACCGTGTTTGACAACTAT TCAGCCAATGTGATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGACACTGCTGGG CAGGAGGACTACGACCGTCTCCGGCCGCTCTCCTATCCACAGACGGACGTCTTCCTCATC TGCTTCTCCCTCGTCAGCCCAGCCTCTTATGAGAACGTCCGCGCCAAGTGGTTCCCAGAA GTGCGGCACCACTGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCTGGACCTGCGG GACGACAAGGACACCATCGAGAAACTGAAGGAGAAGAAGCTGGCTCCCATCACCTACCCG CAGGGCCTGGCACTGGCCAAGGAGATTGACTCGGTGAAATACCTGGAGTGCTCAGCTCTC ACCCAGAGAGGCCTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAG CCCACGCGGCAGCAGAAGCGCGCCTGCAGCCTCCTCTAG Clone variation with respect to NM_002872.3 >OriGene 5' read for NM_002872 unedited
NTGTTCANAATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGCT GTCACCACCGACACTCTCCAGGCTCCGGACACGATGCAGGCCATCAAGTGTGTGGTGGTG GGAGATGGGGCCGTGGGCAAGACCTGCCTTCTCATCAGCTACACCACCAACGCCTTTCCC GGAGAGTACATCCCCACCGTGTTTGACAACTATTCAGCCAATGTGATGGTGGACAGCAAG CCAGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCG CTCTCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCT TATGAGAACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCACTGCCCCAGCACACCC ATCATCCTGGTGGGCACCAAGCTGGACCTGCGGGACGACAAGGACACCATCGAGAAACTG AAGGAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATT GACTCGGTGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGGCCTGAAAACCGTGTTC GACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGC AGCCTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCCAGAT CCCCACCCAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCCCTCCTGTGGCGTTTCT TAACAGATGGCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGGAGGCCTNCTGAGCCA NGAACGTGCAATTTGCAGTGCTGCATNCCAAGCCCTCATGCTCTGCTTCTGAGGCCAGAG GNGAGCCCAGACCATTAGCC >OriGene 3' read for NM_002872 unedited
CCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAATCAATAAATTTATTTTCTGCT TAAGCAGGTTGAGTTGGGTTTTCTATTTGCAATAGCAAAAGTCCTGACTGGCAAGGTTTA AAAGTTTGAAGACTCTCACAGGTAAGTGCAGCTCAAGATCCTGTGAGTGCAGCAGAAAGT CTTAAGAAATGGCAGGGGCTGGTTGAACCCATATTTTCCATTGGCTGAGCAGATATCCCC AGAGGCGTAGAAAATTAAATTTGTTTTATGTTGTTCCAAAAGAGGAGAACTGAGGCCAGA GGAGCACACTTCTGAGACACTCATTTTTGCTGGGTAGAGGAACTCTCTGGCAAGCAGGAC CATCGATATTAGAGCAGCTGGCCTCAGGAGGGAGTAAGAGCCCCATCCCTGAAGGTACAC AAGTTGTGGCAGCAACCATCTGGCCTGCAGTTTCCATAGGGGAGTCATGCGTGGGGTGGG ACTGGAGTGAACGGGTAGATGCTTCCACATGCGGCAGTTGGCACTGACGGCAGGAACACG GAGGTGGCTTAATGGGTCCTGAGGCTCCCCTCTGGCCCTCATGAAGGCAGGAGCATGATG GGCTTGNGATGCATCACCTGCAAATTTGCACGTTCCTGGCCTCATGATGCCTNCAGTACA GAAAAGACCATCAACGAAGCTCTGCAGCCATCTGCTAAGAAACGCCACATGGAGGGGACA GCATGGCCAGCCCGGGTGCCATCAGGCTTTGGGTGGGGATCCTGGNAGATCANACCCATC TATGTGGGAGCGCTGGGGTGCACCNCTATAGGAGCTGCANGCGCGCTTCTGCTGCCGCGT GGGCTGATGCACATCACGGCCGGNATGGCTCGTCGAACACGTTTNAGGCCTCTCTGGGTG AGAGCTGACACTTCCAGTTTTCACCGGTNAATCTCCTGGCCNTGCCAGNCCTGCGGTAGT GATGGAGCANCTCTTTNCTCATTCTCGAGGGCCTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002872 |
| Insert Size | 1530 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002872.3, NP_002863.1 |
| RefSeq Size | 1516 bp |
| RefSeq ORF | 579 bp |
| Locus ID | 5880 |
| UniProt ID | P15153 |
| Domains | ras, RAN, RAS, RHO, RAB |
| Protein Families | Druggable Genome |
| Protein Pathways | Adherens junction, Axon guidance, B cell receptor signaling pathway, Chemokine signaling pathway, Colorectal cancer, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Pancreatic cancer, Pathways in cancer, Regulation of actin cytoskeleton, VEGF signaling pathway, Viral myocarditis, Wnt signaling pathway |
| Gene Summary | This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification of the Catalytic Site of Phospholipase D2 (PLD2) Newly Described Guanine Nucleotide Exchange Factor Activity
,Madhu Mahankali, Karen M. Henkels, Gerald Alter, and Julian Gomez-Cambronero,
J. Biol. Chem., Nov 2012; 287: 41417 - 41431.
[RAC2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200304 | RAC2 (Myc-DDK-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2) |
CNY 3,600.00 |
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| RC200304L1 | Lenti-ORF clone of RAC2 (Myc-DDK-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2) |
CNY 6,000.00 |
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| RC200304L2 | Lenti-ORF clone of RAC2 (mGFP-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2) |
CNY 6,840.00 |
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| RC200304L3 | Lenti-ORF clone of RAC2 (Myc-DDK-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2) |
CNY 6,000.00 |
|
| RC200304L4 | Lenti-ORF clone of RAC2 (mGFP-tagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2) |
CNY 6,840.00 |
|
| RG200304 | RAC2 (tGFP-tagged) - Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2) |
CNY 5,200.00 |
