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PABPC4 (NM_003819) Human Untagged Clone
CAT＃: SC117732
PABPC4 (untagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 2
CNY 4,800.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APP-1; APP1; iPABP; PABP4 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117732 sequence for NM_003819 edited (data generated by NextGen Sequencing)
ATGAACGCTGCGGCCAGCAGCTACCCCATGGCCTCCCTGTACGTGGGCGACCTGCATTCG GACGTCACCGAGGCCATGCTGTACGAAAAGTTCAGCCCCGCGGGGCCTGTGCTGTCCATC CGGGTCTGCCGCGATATGATCACCCGCCGCTCCCTGGGCTATGCCTACGTCAACTTCCAG CAGCCGGCCGACGCTGAGCGGGCTTTGGACACCATGAACTTTGATGTGATTAAGGGAAAG CCAATCCGCATCATGTGGTCTCAGAGGGATCCCTCTTTGAGAAAATCTGGTGTGGGAAAC GTCTTCATCAAGAACCTGGACAAATCTATAGATAACAAGGCACTTTATGATACTTTTTCT GCTTTTGGAAACATACTGTCCTGCAAGGTGGTGTGTGATGAGAACGGCTCTAAGGGTTAT GCCTTTGTCCACTTCGAGACCCAAGAGGCTGCCGACAAGGCCATCGAGAAGATGAATGGC ATGCTCCTCAATGACCGCAAAGTATTTGTGGGCAGATTCAAGTCTCGCAAAGAGCGGGAA GCTGAGCTTGGAGCCAAAGCCAAGGAATTCACCAATGTTTATATCAAAAACTTTGGGGAA GAGGTGGATGATGAGAGTCTGAAAGAGCTATTCAGTCAGTTTGGTAAGACCCTAAGTGTC AAGGTGATGAGAGATCCCAATGGGAAATCCAAAGGCTTTGGCTTTGTGAGTTACGAAAAA CACGAGGATGCCAATAAGGCTGTGGAAGAGATGAATGGAAAAGAAATAAGTGGTAAAATC ATATTTGTAGGCCGTGCACAAAAGAAAGTAGAACGGCAGGCAGAGTTAAAACGGAAATTT GAACAGTTGAAACAGGAGAGAATTAGTCGATATCAGGGGGTGAATCTCTACATTAAGAAC TTGGATGACACTATTGATGATGAGAAATTAAGGAAAGAATTTTCTCCTTTTGGATCAATT ACCAGTGCTAAGGTAATGCTGGAGGATGGAAGAAGCAAAGGGTTTGGCTTCGTCTGCTTC TCATCTCCTGAAGAAGCAACCAAAGCAGTCACTGAGATGAATGGACGCATTGTGGGCTCC AAGCCACTATATGTTGCCCTGGCCCAGAGGAAGGAAGAGAGAAAGGCTCACCTGACCAAC CAGTATATGCAACGAGTGGCTGGAATGAGAGCACTTCCTGCCAATGCCATCTTAAATCAG TTCCAGCCTGCAGCGGGTGGCTACTTTGTGCCAGCAGTCCCACAGGCTCAGGGAAGGCCT CCATATTATACACCTAACCAGTTAGCACAGATGAGGCCTAATCCACGCTGGCAGCAAGGT GGGAGACCTCAAGGCTTCCAAGGAATGCCAAGTGCTATACGCCAGTCTGGGCCTCGTCCA ACTCTTCGCCATCTGGCTCCAACTGGGTCTGAGTGCCCGGACCGCTTGGCTATGGACTTT GGTGGGGCTGGTGCCGCCCAGCAAGGGCTGACTGACAGCTGCCAGTCTGGAGGCGTTCCC ACAGCTGTGCAGAACTTAGCGCCACGCGCTGCTGTTGCTGCTGCTGCTCCCCGGGCTGTT GCCCCCTACAAATACGCCTCCAGTGTCCGCAGCCCTCATCCTGCCATACAGCCTCTGCAG GCACCCCAGCCTGCGGTCCATGTGCAGGGGCAGGAGCCACTGACTGCCTCCATGCTGGCT GCAGCACCCCCCCAGGAACAGAAGCAGATGCTGGGAGAACGCTTGTTCCCACTCATCCAA ACAATGCATTCAAATCTGGCTGGGAAGATCACGGGAATGCTGCTGGAGATAGACAACTCT GAGCTGCTGCACATGTTAGAGTCCCCCGAGTCTCTCCGCTCCAAGGTGGATGAAGCTGTA GCAGTTCTACAGGCTCATCATGCCAAGAAAGAAGCTGCCCAGAAGGTGGGCGCTGTTGCT GCTGCTACCTCTTAG Clone variation with respect to NM_003819.3 >OriGene 5' read for NM_003819 unedited
TTGTAATACGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGGAAGAATAAAAATAA TCTGAAAACGCTTCAAAATCCTGGAAAAAAAAAAAGGAAAAGAAAAAACGAATCCTCGGA GAACCCGCGGGGAAGTCACTTTCGTACGCTTCCGGCCTGCCCCGCGCCCGCCGCCGCAGC GCTTGGCGTCCGTCGGTCTCCGTCCGTCGGTCCGGGGGTGAGCCGCCCGCCCGGCCCGCC GTGCCCTCCCCCCGCTCGGGCCCCGAGCCCCGCGCCCCGCGCCTGCCCCGGCGCACCACG TGTCCGTGCTGCCCTTCGCCGCCCGCCCGGGGCTCGCCGAGTCGGCGCCCACAAAGATTT GGTTTCCCTCTGCCCCGGCGGTTGTAATCTTAAACCGCCGGAGCCCGAGGCCTATATTTA TAGAGAAACGCGTGTCCCCGAGGCCGCCGTGGGCAGCGTCCGGTCGCCTCTTAAAGGATT TTTACCCTTCGGAAGGGGATTCCCCGTTTAATTTTTTTCCTACTTTGATTTTTTGAAATT TGGAGCTTCGCACCAGGACCGCGGAGAAGTGCAAAGTCGCGGNGAGGGCCGTATTGTGCG GAGAGCCTTTTGTCTGCGGTGCTGCGGCCGTGGGAGCCGGCCCCCGCCTTCCGTTTCCGT CCCGTCTCCAGCCCGNCGACTNCAGCTCGTNCTCGCCGCGCCGGTGCCACCTGTGAGCCG CGGCGCGGGCCCCGGCTTCCGAAGCGCCCCTTTGTCCTGCGGGCGGCCCGATAAGAAAGT CTCCTGGCGGNGCTCGGGTGGTGGNNGGCCGNNNAAAAAAAAAAACNCTTNNNNCCAACA ANCTACCCAATGGCCTTCCTGTACGTGGGCGACCTGCATCCGGACGGTACCGAGCCATGC TGTACCAAAAGTCAGCCCCGGGGGGCCTGGCCTGTCCATCGGGGTTTGGCGGGAAATTAC ACC >OriGene 3' read for NM_003819 unedited
CCGCACCTGNATGTACGAGTTTTTTTCTTTTTTTTTTATGGAGATTTTTTTTTTTATTGG GAAACGTAAGACTTGGGTACATCAAATAAAACCAATTTCTGGGGGGAAAAAATCAAAACC CACAATAAAAAAAAAGTTAACACTGTCTGGGCCACAGCAGAACCCAAAGAACATATTCGT ATAATTCGAAAAATTCTAGGTGCTTCATAATTGACCTTTTGATACAAAATGACCTATTAA ATTTGCAATTTGTAATCCTTGGTGTTGAGGTCCATAGGACAAGCTAGGAAGTCTTCAAAC CTTGAGTTGAATTCCATAAGGGGTTATTTGGCTTTTGAATCGGTTTTTCCTTGTCTAAGA GGTAGCAGCAGCAACAGCGCCCACCTTCTGGGCAGCTTCTTTCTTGGCATGATGAGCCTG TAGAACTGCTACAGCTTCATCCACCTTGGAGCGGAGAGACTCGGGGGACTCTAACATGTG CAGCAGCTCAGAGTTGTCTATCTTCAGCAGCATTCCCGTGATCTTACCAGCCAGATTTGA ATGCATTGTTTGGATGAGTGGGAACAAGCGTTCTACCAGCATCTGCTTCTGTTCCTGGGG GGGTGCTGCACCCCACCTGGAGGCAGTCAGTGGTTACTGCCCCTGCACATGGACCGCAAG CTGGGGTGCCTGCTGAAGGAATCAAAAGCACAGCTTCTTTTACCTCAAGTGGAAAAGGGG AAATCCTTTAAACATTCTGCCTGTGAACCTCACTGCACAGGCGTATGCCAGATGAGGCCG GGCCCCTGGAGCCTATTTGTAGGGCACCGCCCGGGAGCACTACAGCAACAGAACCCGTGC CGCTAATTCTGCACCTCGGGGGACCCCACAAAATGCAGCTGTAATTACCCTTGTGGGCGC GCACCCCCCCAATTCTAATCCAGGGTTCGGGCACCTAAACCCCTTTGGATGGTAAAGGAG CCCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003819 |
| Insert Size | 3420 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003819.2, NP_003810.1 |
| RefSeq Size | 3065 bp |
| RefSeq ORF | 1935 bp |
| Locus ID | 8761 |
| UniProt ID | Q13310 |
| Domains | RRM, PABP, RRM_1 |
| Gene Summary | Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] Transcript Variant: This variant (2) lacks an in-frame segment in the coding region, as compared to variant 1. The resulting isoform 2 lacks an internal segment, as compared to isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219691 | PABPC4 (Myc-DDK-tagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 2 |
CNY 5,700.00 |
|
| RC219691L3 | Lenti-ORF clone of PABPC4 (Myc-DDK-tagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 2 |
CNY 7,600.00 |
|
| RC219691L4 | Lenti-ORF clone of PABPC4 (mGFP-tagged)-Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 2 |
CNY 7,600.00 |
|
| RG219691 | PABPC4 (tGFP-tagged) - Human poly(A) binding protein, cytoplasmic 4 (inducible form) (PABPC4), transcript variant 2 |
CNY 6,270.00 |
