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Dynamin 2 (DNM2) (NM_004945) Human Untagged Clone
CAT＃: SC117045
DNM2 (untagged)-Human dynamin 2 (DNM2), transcript variant 3
CNY 6,352.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004945, the custom clone sequence may differ by one or more nucleotides
ATGGGCAACCGCGGGATGGAAGAGCTGATCCCGCTGGTCAACAAACTGCAGGACGCCTTCAGCTCCATCG GCCAGAGCTGCCACCTGGACCTGCCGCAGATCGCTGTAGTGGGCGGCCAGAGCGCCGGCAAGAGCTCGGT GCTGGAGAACTTCGTGGGCCGGGACTTCCTTCCCCGCGGTTCAGGAATCGTCACCCGGCGGCCTCTCATT CTGCAGCTCATCTTCTCAAAAACAGAACATGCCGAGTTTTTGCACTGCAAGTCCAAAAAGTTTACAGACT TTGATGAAGTCCGGCAGGAGATTGAAGCAGAGACCGACAGGGTCACGGGGACCAACAAAGGCATCTCCCC AGTGCCCATCAACCTTCGAGTCTACTCGCCACACGTGTTGAACTTGACCCTCATCGACCTCCCGGGTATC ACCAAGGTGCCTGTGGGCGACCAGCCTCCAGACATCGAGTACCAGATCAAGGACATGATCCTGCAGTTCA TCAGCCGGGAGAGCAGCCTCATTCTGGCTGTCACGCCCGCCAACATGGACCTGGCCAACTCCGACGCCCT CAAGCTGGCCAAGGAAGTCGATCCCCAAGGCCTACGGACCATCGGTGTCATCACCAAGCTTGACCTGATG GACGAGGGCACCGACGCCAGGGACGTCTTGGAGAACAAGTTGCTCCCGTTGAGAAGAGGCTACATTGGCG TGGTGAACCGCAGCCAGAAGGATATTGAGGGCAAGAAGGACATCCGTGCAGCACTGGCAGCTGAGAGGAA GTTCTTCCTCTCCCACCCGGCCTACCGGCACATGGCCGACCGCATGGGCACGCCACATCTGCAGAAGACG CTGAATCAGCAACTGACCAACCACATCCGGGAGTCGCTGCCGGCCCTACGTAGCAAACTACAGAGCCAGC TGCTGTCCCTGGAGAAGGAGGTGGAGGAGTACAAGAACTTTCGGCCCGACGACCCCACCCGCAAAACCAA AGCCCTGCTGCAGATGGTCCAGCAGTTTGGGGTGGATTTTGAGAAGAGGATCGAGGGCTCAGGAGATCAG GTGGACACTCTGGAGCTCTCCGGGGGCGCCCGAATCAATCGCATCTTCCACGAGCGGTTCCCATTTGAGC TGGTGAAGATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGG AGTCAGGACCGGGCTTTTCACCCCGGACTTGGCATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTG AAAGAGCCCTGTCTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATACAGTTAGGCAGTGTACCA GTAAGCTCAGTTCCTACCCCCGGTTGCGAGAGGAGACAGAGCGAATCGTCACCACTTACATCCGGGAACG GGAGGGGAGAACGAAGGACCAGATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCAT GAGGACTTCATCGGGTTTGCCAATGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCA ATCAGGTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTA CTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAGGAGAAAGAGAAGAAGTACATG CTGCCTCTGGACAACCTCAAGATCCGTGATGTGGAGAAGGGCTTCATGTCCAACAAGCACGTCTTCGCCA TCTTCAACACGGAGCAGAGAAACGTCTACAAGGACCTGCGGCAGATCGAGCTGGCCTGTGACTCCCAGGA AGACGTGGACAGCTGGAAGGCCTCGTTCCTCCGAGCTGGCGTCTACCCCGAGAAGGACCAGGCAGAAAAC GAGGATGGGGCCCAGGAGAACACCTTCTCCATGGACCCCCAACTGGAGCGGCAGGTGGAGACCATTCGCA ACCTGGTGGACTCATACGTGGCCATCATCAACAAGTCCATCCGCGACCTCATGCCAAAGACCATCATGCA CCTCATGATCAACAATACGAAGGCCTTCATCCACCACGAGCTGCTGGCCTACCTATACTCCTCGGCAGAC CAGAGCAGCCTCATGGAGGAGTCGGCTGACCAGGCACAGCGGCGGGACGACATGCTGCGCATGTACCATG CCCTCAAGGAGGCGCTCAACATCATCGGTGACATCAGCACCAGCACTGTGTCCACGCCTGTACCCCCGCC TGTCGATGACACCTGGCTCCAGAGCGCCAGCAGCCACAGCCCCACTCCACAGCGCCGACCGGTGTCCAGC ATACACCCCCCTGGCCGGCCCCCAGCAGTGAGGGGCCCCACTCCAGGGCCCCCCCTGATTCCTGTTCCCG TGGGGGCAGCAGCCTCCTTCTCGGCGCCCCCAATCCCATCCCGGCCTGGACCCCAGAGCGTGTTTGCCAA CAGTGACCTCTTCCCAGCCCCGCCTCAGATCCCATCTCGGCCAGTTCGGATCCCCCCAGGGATTCCCCCA GGAGTGCCCAGCAGAAGACCCCCTGCTGCGCCCAGCCGGCCCACCATTATCCGCCCAGCCGAGCCATCCC TGCTCGACTAG >OriGene 5' read for NM_004945 unedited
GGGTCAACATTTGTATACGACTCACTATAGGGCGGCCGCGATTCGGCCGAGGCCGAGCCG GGAGCGGGCGTCTTGCCGAGGCCCGGGCGGGCGGGGAGCAACGGCTACAGACGCCGCGGG GCCAGGTCGTTGAGGGTCGGCGGCGGGCGAGGAGCGCAGGGCGCTCGGGCCGGGGGCCGC CGGCGCCATGGGCAACCGCGGGATGGAAGAGCTGATCCCGCTGGTCAACAAACTGCAGGA CGCCTTCAGCTCCATCGGCCAGAGCTGCCACCTGGACCTGCCGCAGATCGCTGTAGTGGG CGGCCAGAGCGCCGGCAAGAGCTCGGTGCTGGAGAACTTCGTGGGCCGGGACTTCCTTCC CCGCGGTTCAGGAATCGTCACCCGGCGGCCTCTCATTCTGCAGCTCATCTTCTCAAAAAC AGAACATGCCGAGTTTTTGCACTGCAAGTCCAAAAAGTTTACAGACTTTGATGAAGTCCG GCAGGAGATTGAAGCAGAGACCGACAGGGTCACGGGGACCAACAAAGGCATCTCCCCAGT GCCCATCAACCTTCGAGTCTACTCGCCACACGTGTTGAACTTGACCCTCATCGACCTCCC GGGTATCACCAAGGTGCCTGTGGGCGACCAGCCTCCAGACATCGAGTACCAGATCAAGGA CATGATCCTGCAGTTCATCAGCCGGGAGAGCAGCCTCATTCTGGCTGTCACGCCCGCCAA CATGGACCTGGCCAACTCCGACGCCCTCAAGCTGGCCAAGGAAAGTCGATCCCCCAGGCC TACGGACCATTCGGTGTCATCACCAAGCTTGACCTGATGGACGAGGGCACCGACGCCAGG GACGTCCTGGAGAACAGTTGCTCCCGTTGAGAAGAGCTACATTGGCGGTGGTGACCGCAG CCAGAAGATATGN >OriGene 3' read for NM_004945 unedited
NTTCNTTGNCCGCGGCCGCAATCTAGGATCGAGNTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTAACCAGCAGGGTCTTCCTTTTATTTTAGTTTATTAATAAAATACAGAGGGCAG GCACTTACAGGGGTCAAACTGACCGAGGAGTGGGTGAGGTCTCCTAAAAAAGAGGCCGCC CTGGGCCCACCCATCAGGGAGGCATGGGCGGAAGCTGAAAGGCCCCCAAAACCCCCCGCC ACCACCACCCACATAGCCCAAGCCCAGCCACCCTGGGGGACCCAGGAGGAGGAGGAGGAA AGGAATAGGGCAAGGCCGGCCCGGGCCAACGGTTCCGGGCCTAGCAAAGGCACCTTTGGC AGCCGAGGCTGGGCCAGGCTCAGGCTGTGTGGTTAATATGGCCGGAAAGGACTATGTACA CCTCAGGCCTGCCAGCTGGGCACTACCGAGCCCACTGGGCCAGGCTTGCCGTTGGGGAGC TCCTGCTAAGGGGAAGTTGATATACCCCTGCACCCCAGCAAGGCCTGGGGATGTAGGCGC CCTTGGTGCCCGCACTTATAGAAGGCCTGCCCTACATGGGCTTTCCCAGCCCAAGAAGAC CTTGGTAGAGTCCCCCCCAGCCTGGACCCCTCATTCAGGATGGTGTCAAGGGTTCTGGGT CCCCCCTCTGCACCCTGAGACTCCATCCCCCAAAGTGCAACACCCCAGCGCCCCCTGCCT GGAGCTCCAGGGCCCCTTTGCGCAGGGCGGGGTCCAGCCAGGCACAGGGGCCGGCCCTGA ACGGGGGCAGCGTAAGGAAAAGCCAGGGCTGCCCCTGAAAGCCTGTCCCACATAGGGCGG GGGGAGGCCCCAAACACTGAACTCCTGCCCCGGGTTCCGTGAGGCCCCCCGAAGCAGCCC CCTTGAGGCCAATCAACCAGGATGGCTCGTTGCCGTAAATGGGGCCC |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_004945 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004945.2, NP_004936.2 |
| RefSeq Size | 3621 bp |
| RefSeq ORF | 2601 bp |
| Locus ID | 1785 |
| UniProt ID | P50570 |
| Domains | dynamin_2, dynamin, PH, GED |
| Protein Families | Transcription Factors |
| Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
| Gene Summary | Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010] Transcript Variant: This variant (3) lacks an alternate in-frame exon, compared to variant 1. The resulting protein (isoform 3) is shorter, compared to isoform 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208525 | DNM2 (Myc-DDK-tagged)-Human dynamin 2 (DNM2), transcript variant 3 |
CNY 3,990.00 |
|
| RC208525L3 | Lenti ORF clone of Human dynamin 2 (DNM2), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208525L4 | Lenti ORF clone of Human dynamin 2 (DNM2), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG208525 | DNM2 (tGFP-tagged) - Human dynamin 2 (DNM2), transcript variant 3 |
CNY 4,370.00 |
|
| SC324242 | DNM2 (untagged)-Human dynamin 2 (DNM2), transcript variant 3 |
CNY 6,352.00 |
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