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PAICS (NM_006452) Human Untagged Clone
CAT＃: SC111158
PAICS (untagged)-Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADE2; ADE2H1; AIRC; PAIS |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111158 sequence for NM_006452 edited (data generated by NextGen Sequencing)
ATGGCGACAGCTGAGGTACTGAACATTGGTAAAAAATTATATGAGGGTAAAACAAAAGAA GTCTACGAATTGTTAGACAGTCCAGGAAAAGTCCTCCTGCAGTCCAAGGACCAGATTACA GCAGGAAATGCAGCTAGAAAAAACCACCTGGAAGGAAAAGCTGCAATCTCAAATAAAATC ACCAGTTGTATTTTTCAGTTATTACAGGAAGCAGGTATTAAAACTGCCTTCACCAGAAAA TGTGGGGAGACAGCTTTCATTGCACCGCAGTGTGAAATGATTCCAATTGAATGGGTTTGC AGAAGAATAGCAACTGGTTCTTTTCTCAAAAGAAATCCTGGTGTCAAGGAAGGATATAAG TTTTACCCACCTAAAGTGGAGTTGTTTTTCAAGGATGATGCCAATAATGACCCACAGTGG TCTGAGGAACAGCTGATTGCTGCAAAATTTTGCTTTGCTGGACTTCTTATAGGCCAGACT GAAGTGGATATCATGAGTCATGCTACACAGGCTATATTTGAAATACTGGAGAAATCCTGG TTGCCCCAGAATTGTACACTGGTTGATATGAAGATTGAATTTGGTGTTGATGTAACCACC AAAGAAATTGTTCTTGCTGATGTTATTGACAATGATTCCTGGAGACTCTGGCCATCAGGA GATCGAAGCCAACAGAAAGACAAACAGTCTTATCGGGACCTCAAAGAAGTAACTCCTGAA GGGCTCCAAATGGTAAAGAAAAACTTTGAGTGGGTTGCAGAGAGAGTAGAGTTGCTTTTG AAATCAGAAAGTCAGTGCAGGGTTGTAGTGTTGATGGGCTCTACTTCTGATCTTGGTCAC TGTGAAAAAATCAAGAAGGCCTGTGGAAATTTTGGCATTCCATGTGAACTTCGAGTAACA TCTGCGCATAAAGGACCAGATGAAACTCTGAGGATTAAAGCTGAGTATGAAGGGGATGGC ATTCCTACTGTATTTGTGGCAGTGGCAGGCAGAAGTAATGGTTTGGGACCAGTGATGTCT GGGAACACTGCATATCCAGTTATCAGCTGTCCTCCCCTCACACCAGACTGGGGAGTTCAG GATGTGTGGTCTTCTCTTCGACTACCCAGTGGTCTTGGCTGTTCAACCGTACTTTCTCCA GAAGGATCAGCTCAATTTGCTGCTCAGATATTTGGGTTAAGCAACCATTTGGTATGGAGC AAACTGCGAGCAAGCATTTTGAACACATGGATTTCCTTGAAGCAGGCTGACAAGAAAATC AGAGAATGTAATTTATAA Clone variation with respect to NM_006452.3 >OriGene 5' read for NM_006452 unedited
TTCAAATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGGTTCTGC CTCGCTTCCCGGCGCGGTCGCAGCCCTCAGCCCACTTAGGATAATGGCGACAGCTGAGGT ACTGAACATTGGTAAAAAATTATATGAGGGTAAAACAAAAGAAGTCTACGAATTGTTAGA CAGTCCAGGAAAAGTCCTCCTGCAGTCCAAGGACCAGATTACAGCAGGAAATGCAGCTAG AAAAAACCACCTGGAAGGAAAAGCTGCAATCTCAAATAAAATCACCAGTTGTATTTTTCA GTTATTACAGGAAGCAGGTATTAAAACTGCCTTCACCAGAAAATGTGGGGAGACAGCTTT CATTGCACCGCAGTGTGAAATGATTCCAATTGAATGGGTTTGCAGAAGAATAGCAACTGG TTCTTTTCTCAAAAGAAATCCTGGTGTCAAGGAAGGATATAAGTTTTACCCACCTAAAGT GGAGTTGTTTTTCAAGGATGATGCCAATAATGACCCACAGTGGTCTGAGGAACAGCTGAT TGCTGCAAAATTTTGCTTTGCTGGACTTCTTATAGGCCAGACTGAAGTGGATATCATGAG TCATGCTACACAGGCTATATTTGAAATACTGGAGAAATCCTGGTTGCCCCAGAATTGTAC ACTGGTTGATATGAAGATTGAATTTGGTGTNGATGNTACCACCAAAAGAATTNNGTCTGC TGNATGTATTTGACATGATTCCTGGAGACTCTGGCCATCAGGAGATCGAAGCCCNACAGA AGAACAACAGTCTTATCGGGACCTCAAAGAAGTACTCCCTGAGGGCNNTCAATGGNTAAG NAAAAACTTGAGTGGGTTGCANAGAGAGTAGAGTTGCTTTTTGAATCAGAAGTCANTGCA GGNTTGTANTGGTGAGGGCTCTACTTCTGATCTGGGTCACTGTGAAAAATCAGAAAGA >OriGene 3' read for NM_006452 unedited
ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTATTCACTAATACA TTTTATTTGTGTTCTCTAATTTAAAATTACCTTTTCATCTTGCTTGATTTTCCTTCAGCT AAATTAGAAATTTGTAGTTTTTCCCCTAAAAAATTCAATGGCATTCTTTCTTATAAATTA CATTCTCTGATTTTCTTGTCAGCCTGCTTCAAGGAAATCCATGTGTTCAAAATGCTTGCT CGCAGTTTGCTCCATACCAAATGGTTGCTTAACCCAAATATCTGAGCAGCAAATTGAGCT GATCCTTCTGGAGAAAGTACGGTTGAACAGCCAAGACCACTGGGTAGTCGAAGAGAAGAC CACACATCCTGAACTCCCCAGTCTGGTGTGAGGGGAGGACAGCTGATAACTGGATATGCA GTGTTCCCAGACATCACTGGTCCCAAACCATTACTTCTGCCTGCCACTGCCACAAATACA GTAGGAATGCCATCCCCTTCATACTCAGCTTTAATCCTCAGAGTTTCATCTGGTCCTTTA TGCGCAGATGTTACTCGAAGTTCACATGGAATGCCAAAATTTCCACAGGCCTTCTTGATT TTTTCACAGTGACCAAGATCAGAAGTAGAGCCCATCAACACTACAACCCTGCACTGACTT TCTGATTTCAAAAGCAACTCTACTCTCTCTGCACCCACTCAAAGTTTTTCTTTACCATTT GGAGCCCTTCANGAGTTACTTCTTTGAGGTCCCGNATAGACTGTTTGTCTTTCTGTGGCC TTCGATCTCCTGATGGCCANAGTCTCCAGAAATCATTGTCAATAACATCAGCCAGAACAA TTTCTTTGGGTGGTACATCACACCAAATTCAATCTTCATATCAACCAGTGTACAATTCTG GGGCAACCAGGATTCTCCAGTATTNACAAATAGCCTGGTAACATGACTC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006452 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_006452.2, NP_006443.1 |
| RefSeq Size | 3322 bp |
| RefSeq ORF | 1278 bp |
| Locus ID | 10606 |
| UniProt ID | P22234 |
| Domains | AIRC, SAICAR_synt |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Purine metabolism |
| Gene Summary | This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon in the CDS, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Variants 2 and 3 encode the same isoform. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215225 | PAICS (Myc-DDK-tagged)-Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2 |
CNY 3,656.00 |
|
| RC215225L1 | Lenti ORF clone of Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215225L2 | Lenti ORF clone of Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC215225L3 | Lenti ORF clone of Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215225L4 | Lenti ORF clone of Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG215225 | PAICS (tGFP-tagged) - Human phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), transcript variant 2 |
CNY 4,370.00 |
