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Estrogen Related Receptor gamma (ESRRG) (NM_001438) Human Untagged Clone
CAT＃: SC102184
ESRRG (untagged)-Human estrogen-related receptor gamma (ESRRG), transcript variant 1
CNY 3,656.00
CNY 7,320.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ERR-gamma; ERR3; ERRg; ERRgamma; NR3B3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC102184 sequence for NM_001438 edited (data generated by NextGen Sequencing)
ATGGATTCGGTAGAACTTTGCCTTCCTGAATCTTTTTCCCTGCACTACGAGGAAGAGCTT CCCTGCAGAATGTCAAACAAAGATCGACACATTGATTCCAGCTGTTCGTCCTTCATCAAG ACGGAACCTTCCAGCCCAGCCTCCCTGACGGACAGCGTCAACCACCACAGCCCTGGTGGC TCTTCAGACGCCAGTGGGAGCTACAGTTCAACCATGAATGGCCATCAGAACGGACTTGAC TCGCCACCTCTCTACCCTTCTGCTCCTATCCTGGGAGGTAGTGGGCCTGTCAGGAAACTG TATGATGACTGCTCCAGCACCATTGTTGAAGATCCCCAGACCAAGTGTGAATACATGCTC AACTCGATGCCCAAGAGACTGTGTTTAGTGTGTGGTGACATCGCTTCTGGGTACCACTAT GGGGTAGCATCATGTGAAGCCTGCAAGGCATTCTTCAAGAGGACAATTCAAGGCAATATA GAATACAGCTGCCCTGCCACGAATGAATGTGAAATCACAAAGCGCAGACGTAAATCCTGC CAGGCTTGCCGCTTCATGAAGTGTTTAAAAGTGGGCATGCTGAAAGAAGGGGTGCGTCTT GACAGAGTACGTGGAGGTCGGCAGAAGTACAAGCGCAGGATAGATGCGGAGAACAGCCCA TACCTGAACCCTCAGCTGGTTCAGCCAGCCAAAAAGCCATATAACAAGATTGTCTCACAT TTGTTGGTGGCTGAACCGGAGAAGATCTATGCCATGCCTGACCCTACTGTCCCCGACAGT GACATCAAAGCCCTCACTACACTGTGTGACTTGGCCGACCGAGAGTTGGTGGTTATCATT GGATGGGCGAAGCATATTCCAGGCTTCTCCACGCTGTCCCTGGCGGACCAGATGAGCCTT CTGCAGAGTGCTTGGATGGAAATTTTGATCCTTGGTGTCGTATACCGGTCTCTTTCATTT GAGGATGAACTTGTCTATGCAGACGATTATATAATGGACGAAGACCAGTCCAAATTAGCA GGCCTTCTTGATCTAAATAATGCTATCCTGCAGCTGGTAAAGAAATACAAGAGCATGAAG CTGGAAAAAGAAGAATTTGTCACCCTCAAAGCTATAGCTCTTGCTAATTCAGACTCCATG CACATAGAAGATGTTGAAGCCGTTCAGAAGCTTCAGGATGTCTTACATGAAGCGCTGCAG GATTATGAAGCTGGCCAGCACATGGAAGACCCTCGTCGAGCTGGCAAGATGCTGATGACA CTGCCACTCCTGAGGCAGACCTCTACCAAGGCCGTGCAGCATTTCTACAACATCAAACTA GAAGGCAAAGTCCCAATGCACAAACTTTTTTTGGAAATGTTGGAGGCCAAGGTCTGA Clone variation with respect to NM_001438.3 62 t=>c;957 g=>a >OriGene 5' read for NM_001438 unedited
TCACAATAGGNATACGATTACTATAGGCGGCCGCGAATTCGGCACGAGGCTTGATTAGGA GAGTGTGAGAGCTTTGGTCCCAACTGGCTGTGCCTATAGGCTTGTCACTAGGAGAACATT TGTGTTAATTGCACTGTGCTCTGTCAAGGAAACTTTGATTTATAGCTGGGGTGCACAAAT AATGGTTGCCGGTCGCACATGGATTCGGTAGAACTTTGCCTTCCTGAATCTTTTTCCCTG CACTACGAGGAAGACTTTCCCTGCAGAATGTCAAACAAAGATCGACACATTGATTCCAGC TGTTCGTCCTTCATCAAGACGGAACCTTCCAGCCCAGCCTCCCTGACGGACAGCGTCAAC CACCACAGCCCTGGTGGCTCTTCAGACGCCAGTGGGAGCTACAGTTCAACCATGAATGGC CATCAGAACGGACTTGACTCGCCACCTCTCTACCCTTCTGCTCCTATCCTGNGAGGTAGT GGGCCTGTCAGGAAACTGTATGATGACTGCTCCAGCACCATTGTTGAAGATCCCCAGACC AAGTGTGAATACATGCTCAACTCGATGCCCAAGAGACTGTGTTTAGTGTGTGGTGACATC GCTTTTGGGTACCACTATGGNGTAGCATCATGTGAAGCCTGCAAGCATTCTTCAAGAAGA CAATTCAAGGCATATGAATACAGCTGCCCTGCCACGAATGAATGTGAAATCACAAAACGC AGACGTAAAATCTGCCCAGCTTGCCGCTTCATGTAATGTTTAAAAGTGGCCATGCTGAAA GAAGGTGTGCGTCTTGACAGATAACTGGAGGTTCGCCAAAAGTACCAGCCCACGATATAT TGCGNAGAACACCCCTTACCTGACCCTCAGCTGGTTCACCCAGCCCAAAAGTCTTTTACA CGATTGGTTAACATTGTTTGTTGCCTGAACCGGAAAAAATCTATTCATGCCTGAACCTAT TGTCCCCGACAGGACATAN >OriGene 3' read for NM_001438 unedited
GGTACTCTAGGTACGCGGCCGCATTTTAGGATCGAGTTTTATTTCTTTTTTTTTAATTCT GGCATTTGCCTTATTGCCTCTTAAATGATACTGGCTCACAGCTCCTTCTGAGGCAAGGTC TGTGACTTTGCAAACAGGCAGTATCACATTCCTAACCACCATGGCAGCTAGAAATCATAT GGCAATTGTACCTCCCAAGTAGAGAGGTGCACTCCTGACTATTCTACGGATCTATATCTC ATGTGCAGTGCTTATATATGTGACTACTCAGAGTCACTGTAGGTGTAATCTCATCCTTTG TGTCAGTGAACATTTAGGTAAACTGGAGCTCATGTTAAGAAATTGATGTTTGGGACCAGA CTGGCACACAACATAAATTGCATCCGTGATAATATGCACCTTCCCTTCAACTATTGCTTG AGTAAGTTAAATTCCCATATTAATAAATGGCTGAAAAGTGGTAAAGCTGGTACAAAAAAA TCTCCATTTGTAAGAAGAAACAAAACATTTTTAAAAATCTTCCTTCAGGATTCATTTGTC CTTCATTATTGTTCGTAATTGTTCAAAGCCAGCACAAAATTGCAGTATTCTTATTTCTCT TTAGTATTGCATGAATGAATAAAGCTTANACTATTCCCTGAAAAAGTTACATAGTAGCTA AACTAACAAATACCTGGAAGACTTGAAAAAACAATTAAGGAATCAAATGGCTGTTACTGA TCTAGATGGAAAAGCAATGATAAGAAGCAGCCGATGCCACGTTGCCTTAGTTTGTCTAAT TAGAGGCTGCTTCCATGAAATCTAATACTGCACTCAGTCAATTTGTATATGTTGCACTGT ACTTTTAGGAACGTTGGGTTCTCTCTCTTTGGATTCCCTAAACATTGGGGACGGTATGGG TAACAAAAGGTTCACGGGCATCCCTATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001438 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001438.2, NP_001429.2 |
| RefSeq Size | 5253 bp |
| RefSeq ORF | 1377 bp |
| Locus ID | 2104 |
| UniProt ID | P62508 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Gene Summary | This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (1) encodes isoform 1. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218233 | ESRRG (Myc-DDK-tagged)-Human estrogen-related receptor gamma (ESRRG), transcript variant 1 |
CNY 3,656.00 |
|
| RC218233L1 | Lenti ORF clone of Human estrogen-related receptor gamma (ESRRG), transcript variant 1, Myc-DDK-tagged |
CNY 5,990.00 |
|
| RC218233L2 | Lenti ORF clone of Human estrogen-related receptor gamma (ESRRG), transcript variant 1, mGFP tagged |
CNY 5,990.00 |
|
| RC218233L3 | Lenti ORF clone of Human estrogen-related receptor gamma (ESRRG), transcript variant 1, Myc-DDK-tagged |
CNY 5,990.00 |
|
| RC218233L4 | Lenti ORF clone of Human estrogen-related receptor gamma (ESRRG), transcript variant 1, mGFP tagged |
CNY 5,990.00 |
|
| RG218233 | ESRRG (tGFP-tagged) - Human estrogen-related receptor gamma (ESRRG), transcript variant 1 |
CNY 4,470.00 |
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