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Slc8b1 (NM_001017488) Rat Untagged Clone
CAT＃: RN205249
Slc24a6 (untagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug)
CNY 7,410.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Slc24a6 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN205249 representing NM_001017488
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCAGGCAGATGGCTGGATCCGCTCTGGGCGCCTGGCTTCCTCTGTGTGGCTCTGATACTGGAGACGG CATCTGGGGCCGGAGATCTATCCACAAAAGCACATGGACACATCCAGTTTTCAGCCAGAGGTGTCAACCA GACTGCCATGGCAGACTGCCGAGCTGTGTGTAGCCTGAACACATCTGACCGCTGTGACTTTGTCAAGAGG AATCCCGACTGCCACAGCGAGGGGGGCTACCTGGACTACCTCAAGGGCATCTTCTGCTACTTCCCCCCCA ACCTCCTCCCTCTGGCCATCACCCTCTATGTTTTCTGGCTCCTTTACCTCTTTCTGATCCTCGGAGTCAC CGCAGCCAAGTTCTTCTGCCCTAACTTGTCAGCCATCTCCACCAGCCTCAAGCTCTCCCACAACGTGGCA GGTGTCACCTTCCTGGCCTTTGGAAATGGCGCTCCAGACATTTTCAGTGCTCTCGTGGCTTTCTCAGACC CTCGTACTGCTGGCCTGGCCATTGGGGCTCTGTTTGGTGCAGGGGTGCTGGTCACTACTGTGGTGGCTGG TGGCATCACCATCCTGCGTCCCTTCATGGCTGCCTCCAGGCCCTTCCTCAGGGACATCACTTTCTATATG GTGGCCGTGTTCCTCACCTTCACCGCACTCTATCTCGGCAGGATCACACTGGTGTGGGCACTGGGTTACC TGGGCCTCTATGTCTTCTATGTGGTCACGGTCATCATCTGCACTTGGGTCTACCAAAGGCAGCGGAGCAG GTCTTTGGTCCACTCCATATCAGAGACACCAGAGCTACTGACTGATTCAGAAGAGGATCAGATGTCTTCC AACACCAACAGCTATGACTATGGAGAGGAGTACCGGCCTCTGCTGCTGGGTGAGGAGACCACTGGGCAGA TCCTGCTCCAAGCCCTGAATCCCTTGGACTACAGGAAGTGGAGAACTCAGTCGATATCCTGCAAGCTCCT GAAAGTGGCCAAGTTGCCTGTGGAGTTCTTGTTGCTGCTCACGGTACCCGTTGTGGACCCCGACAAGGAT GATCGGAACTGGAAACGGCCACTCAACTGTCTGCAGCTGGTCATCAGCCCCCTGGTCCTGGTCCTGACCC TGCAGTCGGGGGTCTATGGCATCTATGAGATCGGTGGCCTCCTTCCTGTGTGGGCTGTAGTGGTGATCGT GGGCACAGCCCTGGCTTCAGTGACCTTCTTTGCCACATCTAACAGCGAACCCCCTAGACTGCACTGGCTC TTTGCTTTCCTGGGTTTCCTGACCAGCGCCCTGTGGATCAATGCAGCTGCCACGGAGGTGGTGAACATCT TGCGGTCCCTGGGCGTGGTCTTCCGTCTGAGCAACACCGTCCTAGGGCTGACCCTCCTGGCCTGGGGGAA CAGCATTGGAGATGCGTTCTCAGATTTCACGCTGGCCCGCCAGGGATACCCTCGGATGGCCTTCTCTGCC TGTTTTGGCGGCATCATCTTCAATATCCTGGTTGGTGTGGGACTGGGCTGCTTGCTACAAATTGTCCGGA GCCATGCTTCCGAGGTGAAGCTGGAACCAGACGGACTGCTGGTGTGGGTGCTGGCCAGTGCGCTGGGCCT CAGCCTGGTCTTCTCCCTGGTCTCGGTTCCGCTCCAGTGTTTCCAGCTCAGCAAGGCCTACGGCCTCTGC CTCCTCCTCTTCTATATATGTTTCATTGTGGTGGTCCTCCTCACGGAGTTCGGGGTGATTCACTTGAAGG CTGACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001017488 |
| Insert Size | 1758 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001017488.1, NP_001017488.1 |
| RefSeq Size | 2693 bp |
| RefSeq ORF | 1758 bp |
| Locus ID | 498185 |
| UniProt ID | Q6AXS0 |
| Gene Summary | Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion. Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes (By similarity). Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Required for store-operated Ca(2+) entry (SOCE) and Ca(2+) release-activated Ca(2+) (CRAC) channel regulation: sodium transport by SLC8B1 leads to promote calcium-shuttling that modulates mitochondrial redox status, thereby regulating SOCE activity (By similarity). Involved in B-lymphocyte chemotaxis (By similarity). Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+) (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR205249 | Slc24a6 (Myc-DDK-tagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug) |
CNY 7,410.00 |
|
| RR205249L3 | Lenti ORF clone of Slc24a6 (Myc-DDK-tagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug) |
CNY 9,410.00 |
|
| RR205249L4 | Lenti ORF clone of Slc24a6 (mGFP-tagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug) |
CNY 10,260.00 |
