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Neurexin II alpha (NRXN2) (NM_138732) Human Tagged ORF Clone
CAT＃: RG222365
- TrueORF®
NRXN2 (tGFP-tagged) - Human neurexin 2 (NRXN2), transcript variant alpha-2
ORF Plasmid: DDK
"NM_138732" in other vectors (2)
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CNY 17,960.00
货期*
详询
规格
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经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG222365 representing NM_138732
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGTCCGGGAGCCGGTGGCGGCCGACACCGCCGCCGCTGCTGTTGCTGCTGCTGCTGGCGCTGGCGG CGCGCGCGGACGGCCTGGAGTTCGGCGGCGGCCCCGGGCAGTGGGCTCGCTACGCGCGCTGGGCGGGCGC GGCGAGCAGCGGCGAGCTCAGCTTCAGCCTGCGCACCAACGCCACGCGCGCGCTGCTGCTCTACCTGGAC GACGGCGGCGACTGCGACTTCCTGGAGCTGCTGCTGGTGGACGGCCGCCTGCGGCTGCGCTTCACGCTTT CGTGCGCCGAGCCGGCCACGCTGCAGCTGGACACGCCGGTGGCCGACGACCGCTGGCACATGGTGCTGCT GACCCGCGACGCGCGCCGCACGGCGCTGGCGGTGGACGGCGAGGCCCGCGCCGCCGAGGTGCGCTCCAAG CGGCGCGAGATGCAGGTGGCCAGCGACCTGTTCGTGGGCGGCATCCCGCCCGACGTGCGCCTCTCGGCGC TTACGCTGAGCACCGTCAAGTACGAGCCGCCCTTCCGCGGCCTCTTGGCCAACCTGAAGCTGGGCGAGCG GCCCCCCGCGCTGCTGGGCAGCCAGGGCCTGCGCGGCGCCACCGCCGACCCGCTGTGCGCGCCCGCGCGC AACCCCTGCGCCAACGGCGGCCTCTGCACCGTGCTGGCCCCCGGCGAGGTGGGCTGCGACTGCAGCCACA CGGGCTTCGGCGGCAAGTTCTGCAGCGAAGAGGAGCACCCCATGGAAGGTCCGGCTCACCTGACGTTAAA CAGCGAAGGCAAGGAGGAGTTTGTGGCGACCTTCAAAGGCAATGAGTTCTTCTGCTACGACCTGTCACAC AACCCCATCCAGAGCAGCACTGATGAGATCACACTGGCCTTCCGCACCCTGCAACGCAACGGCCTGATGC TGCATACAGGCAAGTCGGCCGACTACGTCAACCTGTCCCTCAAGTCTGGGGCTGTCTGGCTGGTCATCAA CCTAGGCTCAGGTGCCTTCGAGGCCCTTGTGGAACCCGTCAATGGCAAGTTCAACGACAACGCCTGGCAC GACGTCCGGGTCACCCGAAACCTGCGCCAGCACGCAGGGATTGGACACGCTATGGTGACCATCTCGGTGG ACGGGATCCTGACCACCACAGGCTACACGCAGGAGGATTACACCATGCTGGGCTCTGATGACTTCTTCTA CATTGGGGGCAGCCCCAACACAGCTGACCTGCCGGGCTCGCCCGTCAGCAACAACTTCATGGGCTGCCTC AAGGACGTGGTCTATAAGAACAATGACTTCAAATTGGAACTATCCCGCCTGGCAAAGGAAGGGGACCCCA AGATGAAGCTGCAGGGGGACTTGTCATTCCGCTGTGAGGATGTGGCTGCCCTGGACCCTGTGACCTTTGA GAGTCCCGAGGCCTTTGTGGCGCTGCCCCGCTGGAGCGCTAAGCGCACTGGCTCCATCTCCCTAGACTTC CGCACCACCGAGCCCAATGGGCTGCTGCTCTTCAGCCAGGGCCGGCGGGCTGGGGGTGGAGCTGGCAGCC ACAGCTCTGCTCAGCGGGCCGACTACTTTGCCATGGAGCTATTGGACGGCCACCTCTATCTTCTGCTGGA CATGGGATCTGGGGGCATCAAGCTGCGGGCATCCAGCCGCAAGGTCAATGATGGCGAGTGGTGTCACGTG GACTTCCAGAGGGATGGGCGAAAAGGCTCCATCTCAGTGAATAGTCGCAGCACGCCGTTCTTGGCCACTG GAGACAGCGAGATTCTGGACCTGGAGAGTGAGCTGTACCTGGGCGGTCTCCCTGAGGGGGGCCGGGTGGA CCTGCCCCTGCCCCCAGAGGTGTGGACAGCAGCACTCCGGGCAGGCTACGTGGGCTGTGTGCGGGACCTC TTCATAGATGGGCGTAGCCGAGACCTCCGGGGCCTGGCTGAGGCTCAGGGGGCTGTGGGCGTTGCCCCCT TTTGCTCCCGGGAGACGCTGAAGCAGTGTGCATCTGCCCCCTGTCGCAATGGGGGCGTCTGTCGAGAAGG CTGGAACCGCTTCATCTGTGACTGCATCGGGACCGGCTTTCTTGGGCGGGTCTGTGAGAGAGAGGCCACG GTCCTGAGCTACGATGGCTCCATGTACATGAAGATCATGCTGCCTAACGCCATGCACACGGAGGCAGAGG ATGTGTCCCTGCGTTTCATGTCCCAGCGGGCCTACGGACTCATGATGGCCACCACTTCCAGGGAGTCTGC CGACACCCTACGCCTGGAGCTGGATGGGGGGCAGATGAAGCTCACTGTCAACCTCGGTAAAGGCCCCGAA ACGCTGTTTGCGGGGCACAAGCTCAATGACAATGAGTGGCACACGGTGAGGGTGGTCCGGCGTGGCAAGA GCCTGCAGCTGTCTGTGGACAACGTGACTGTGGAGGGACAGATGGCAGGAGCCCATATGCGGCTGGAGTT CCACAACATTGAGACGGGCATCATGACGGAGCGGCGGTTTATCTCCGTGGTGCCCTCCAACTTCATCGGG CATCTGAGTGGGCTCGTGTTCAATGGCCAGCCCTACATGGACCAGTGCAAGGATGGTGACATCACCTACT GTGAGCTCAATGCTCGCTTTGGCCTGCGTGCCATCGTGGCCGATCCCGTCACCTTCAAGAGTCGCAGCAG CTACCTGGCACTCGCCACGCTCCAAGCCTATGCTTCCATGCACCTCTTCTTCCAGTTCAAGACCACGGCC CCTGATGGGCTTCTTCTGTTCAACTCGGGCAACGGCAATGACTTCATTGTCATCGAGCTGGTCAAGGGGT ACATCCACTACGTGTTTGACCTGGGGAATGGCCCGTCCTTGATGAAGGGGAACTCAGACAAACCAGTCAA TGACAACCAGTGGCACAACGTGGTGGTGTCCAGGGACCCAGGCAACGTGCACACGCTCAAGATTGACTCC CGCACTGTCACGCAGCACTCCAATGGCGCCCGAAACCTCGATCTCAAAGGGGAGTTGTACATTGGCGGTC TGAGCAAGAATATGTTCAGCAACCTGCCCAAGCTGGTGGCCTCCCGGGATGGCTTTCAGGGCTGCCTGGC CTCAGTGGACCTCAACGGACGTCTCCCAGACCTCATCGCCGACGCCCTGCACCGCATTGGGCAGGTGGAG AGGGGCTGTGATGGCCCCAGCACCACCTGCACTGAAGAGTCCTGTGCCAACCAGGGCGTCTGCTTGCAGC AGTGGGATGGCTTCACCTGCGACTGCACCATGACTTCCTATGGAGGCCCTGTCTGCAATGATCCCGGGAC CACATACATCTTTGGGAAGGGGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACG AGGATGGATCGCCTGGCCGTGGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGGGTGGACAGCG CCTCCGGCCTTGGAGACTACCTGCAGCTGCACATCGACCAGGGCACCGTGGGGGTGATCTTTAACGTGGG CACGGACGACATTACCATCGACGAGCCCAACGCCATAGTAAGCGACGGCAAATACCACGTGGTGCGCTTC ACTCGAAGCGGCGGCAACGCCACCCTGCAGGTGGACAGCTGGCCGGTCAACGAGCGGTACCCGGCAGGCC GCCAGCTGACCATCTTCAACAGCCAGGCTGCCATCAAGATCGGGGGCCGGGATCAGGGCCGCCCCTTCCA GGGCCAGGTGTCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCTGGCCGCCGAGAGCGACCCCAAT GTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAGGGGCCGTCCGTGCTGCTCAGTGCGGAGACCACGG CCACCACCCTGCTGGCTGACATGGCCACCACCATCATGGAGACTACCACCACCATGGCCACTACCACCAC GCGCCGGGGCCGCTCCCCCACACTGAGGGACAGCACCACCCAGAACACAGATGACCTGCTGGTGGCCTCT GCTGAGTGTCCAAGCGATGATGAGGACCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATTGC CCATTATCACGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTCGTGCCCCCGCCCCC TACCTTCTACCCCTTCCTCACGGGAGTGGGCGCCACCCAAGACACGCTGCCCCCGCCCGCCGCGCGCCGC CCGCCCTCTGGGGGCCCGTGCCAGGCCGAGCGGGACGACAGCGACTGCGAGGAGCCCATCGAGGCCTCGG GCTTCGCCTCCGGGGAGGTCTTTGACTCCAGCCTCCCCCCCACGGACGACGAGGACTTTTACACCACCTT TCCCCTGGTCACGGACCGCACCACCCTCCTGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACA GATGGGGCCACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGGCCCCCAACCTGCCGGCGGGCA AAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGGAGAACCCGCCCTTGGGGCCCGGGGCCCCCACGTC CTTTGAGCCGCGGAGGCCCCCTCCCCTGCGCCCCGGCGTGACCTCAGCCCCCGGCTTCCCCCATCTGCCC ACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCCGGGCGCAGTGGAGGTGATCCGGGAGTCCAGCA GCACCACGGGCATGGTGGTGGGCATTGTGGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCAT GTATAAGTACCGCAATCGTGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACTACATCAGTAACTCG GCCCAGAGCAATGGGGCGGTGGTGAAAGAGAAGGCCCCGGCTGCCCCCAAGACGCCCAGCAAGGCCAAGA AGAACAAAGACAAGGAGTATTATGTC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG222365 representing NM_138732
Red=Cloning site Green=Tags(s) MASGSRWRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTNATRALLLYLD DGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSK RREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANLKLGERPPALLGSQGLRGATADPLCAPAR NPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVATFKGNEFFCYDLSH NPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEALVEPVNGKFNDNAWH DVRVTRNLRQHAGIGHAMVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCL KDVVYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDF RTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHV DFQRDGRKGSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDL FIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGVCREGWNRFICDCIGTGFLGRVCEREAT VLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLGKGPE TLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIG HLSGLVFNGQPYMDQCKDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTA PDGLLLFNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS RTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVE RGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALITYTWPPNDRPST RMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRF TRSGGNATLQVDSWPVNERYPAGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPN VRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVAS AECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRT DGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLP TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNYISNS AQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_138732 |
| ORF Size | 4926 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_138732.3 |
| RefSeq Size | 6413 bp |
| RefSeq ORF | 4929 bp |
| Locus ID | 9379 |
| UniProt ID | Q9P2S2 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
| Gene Summary | This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010] |
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