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T box 2 (TBX2) (NM_005994) Human Tagged ORF Clone
CAT＃: RC208558
- TrueORF®
TBX2 (Myc-DDK-tagged)-Human T-box 2 (TBX2)
ORF Plasmid: tGFP
"NM_005994" in other vectors (6)
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CNY 7,824.00
| Cited in 5 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | VETD |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC208558 representing NM_005994
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGAGAGCCGGCGCTGGCGGCCAGCGCCATGGCTTACCACCCGTTCCACGCGCCACGGCCCGCCGACT TCCCCATGTCCGCCTTTCTGGCGGCGGCGCAGCCCTCCTTCTTCCCGGCACTCGCGCTGCCGCCCGGCGC GCTGGCCAAGCCGCTGCCCGACCCGGGCCTGGCGGGGGCGGCGGCCGCGGCGGCGGCGGCGGCAGCAGCG GCCGAGGCGGGGCTGCACGTCTCGGCACTGGGCCCGCACCCGCCCGCCGCGCATCTGCGCTCCCTCAAGA GCCTGGAGCCCGAGGACGAGGTGGAGGACGACCCCAAGGTGACGCTGGAGGCCAAGGAGCTGTGGGACCA GTTCCACAAGCTAGGCACGGAGATGGTCATCACCAAGTCCGGGAGGCGGATGTTCCCCCCCTTCAAGGTG CGAGTCAGCGGCCTGGACAAGAAGGCCAAGTATATCCTGCTGATGGACATTGTAGCCGCTGACGATTGCC GCTATAAGTTCCACAACTCGCGCTGGATGGTGGCGGGCAAGGCCGACCCTGAGATGCCCAAACGCATGTA CATCCACCCAGACAGCCCAGCCACGGGGGAGCAGTGGATGGCTAAGCCTGTGGCCTTCCACAAGCTGAAG CTGACCAACAACATCTCTGACAAGCACGGCTTCACCATCCTAAACTCCATGCACAAGTACCAGCCGCGCT TCCACATAGTGCGAGCCAACGACATCCTGAAGCTGCCTTACAGCACCTTCCGCACCTACGTGTTCCCGGA GACCGACTTCATCGCCGTCACTGCCTACCAGAATGACAAGATCACACAGCTGAAGATCGACAACAACCCG TTTGCCAAGGGCTTCCGGGACACCGGGAACGGCCGGCGGGAGAAAAGGAAGCAGCTGACGCTGCCGTCTC TACGCTTGTACGAGGAGCACTGCAAACCCGAGCGCGATGGCGCGGAGTCAGACGCCTCGTCGTGCGACCC TCCCCCCGCGCGGGAACCACCCACCTCCCCGGGCGCAGCGCCCAGTCCGCTGCGCCTGCACCGGGCCCGA GCTGAGGAGAAGTCGTGCGCCGCGGACAGCGACCCGGAGCCTGAGCGGTTGAGCGAGGAGCGTGCGGGGG CGCCGCTAGGCCGCAGCCCGGCTCCAGACAGCGCCAGCCCCACTCGCTTGACCGAACCCGAGCGCGCCCG GGAGCGGCGTAGTCCCGAGAGGGGCAAGGAGCCGGCCGAGAGCGGCGGGGACGGCCCGTTCGGCCTGAGG AGCCTGGAGAAGGAGCGCGCCGAAGCTCGGAGGAAGGACGAGGGGCGCAAGGAGGCGGCCGAGGGCAAGG AGCAGGGCCTGGCGCCGCTGGTGGTGCAGACAGACAGTGCGTCCCCCCTGGGCGCCGGACACCTGCCCGG CCTGGCCTTTTCCAGCCACTTGCACGGGCAGCAGTTCTTTGGGCCGCTGGGAGCCGGCCAGCCGCTCTTC CTGCACCCTGGACAGTTCACCATGGGCCCTGGCGCCTTCTCCGCCATGGGCATGGGTCACCTACTGGCCT CGGTGGCAGGCGGCGGCAACGGCGGAGGTGGCGGGCCTGGGACCGCCGCGGGGCTGGACGCAGGCGGGCT GGGTCCCGCGGCCAGCGCAGCAAGCACCGCCGCGCCCTTCCCGTTCCACCTCTCCCAGCACATGCTGGCA TCTCAGGGAATTCCAATGCCCACTTTCGGAGGCCTCTTCCCCTACCCCTACACCTACATGGCAGCAGCAG CCGCAGCCGCCTCGGCTTTGCCCGCCACTAGTGCTGCAGCTGCCGCCGCCGCAGCCGCCGGCTCCCTCTC CCGGAGCCCCTTCCTGGGCAGTGCCCGGCCCCGACTGCGTTTCAGCCCCTATCAGATCCCGGTCACCATC CCGCCTAGCACTAGCCTCCTCACCACCGGGCTGGCCTCTGAGGGCTCCAAGGCCGCTGGTGGAAACAGCC GGGAGCCTAGCCCCCTGCCCGAGCTGGCTCTCCGCAAAGTAGGGGCCCCATCCCGCGGTGCCCTGTCGCC CAGTGGCTCGGCCAAGGAGGCGGCCAATGAACTGCAGAGCATCCAGAGACTGGTGAGTGGGCTGGAGAGC CAGCGAGCCCTCTCCCCAGGCCGGGAGTCGCCCAAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC208558 representing NM_005994
Red=Cloning site Green=Tags(s) MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAA AEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKV RVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLK LTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNP FAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPERDGAESDASSCDPPPAREPPTSPGAAPSPLRLHRAR AEEKSCAADSDPEPERLSEERAGAPLGRSPAPDSASPTRLTEPERARERRSPERGKEPAESGGDGPFGLR SLEKERAEARRKDEGRKEAAEGKEQGLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLF LHPGQFTMGPGAFSAMGMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASAASTAAPFPFHLSQHMLA SQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGSARPRLRFSPYQIPVTI PPSTSLLTTGLASEGSKAAGGNSREPSPLPELALRKVGAPSRGALSPSGSAKEAANELQSIQRLVSGLES QRALSPGRESPK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_005994 |
| ORF Size | 2136 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005994.4 |
| RefSeq Size | 3396 bp |
| RefSeq ORF | 2139 bp |
| Locus ID | 6909 |
| UniProt ID | Q13207 |
| Protein Families | Transcription Factors |
| MW | 74.9 kDa |
| Gene Summary | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008] |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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TBX2 overexpression promotes proliferation and invasion through epithelial-mesenchymal transition and ERK signaling pathway
,Liu, X;Miao, Z;Wang, Z;Zhao, T;Xu, Y;Song, Y;Huang, J;Zhang, J;Xu, H;Wu, J;Xu, H;,
Exp Ther Med
,PubMed ID 30651856
[TBX2]
|
|
Transcriptional repression of the ectodomain sheddase ADAM10 by TBX2 and potential implication for Alzheimer's disease
,Reinhardt, S;Schuck, F;Stoye, N;Hartmann, T;Grimm, MOW;Pflugfelder, G;Endres, K;,
Cell. Mol. Life Sci.
,PubMed ID 30599067
[TBX2]
|
|
TBX2 overexpression promotes proliferation and invasion through epithelial‑mesenchymal transition and ERK signaling pathway
,Liu, X;Miao, Z;Wang, Z;Zhao, T;Xu, Y;Song, Y;Huang, J;Zhang, J;Xu, H;Wu, J;Xu, H;,
Exp Ther Med
[TBX2]
|
|
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes
,Khalil, A;Dekmak, B;Boulos, F;Kantrowitz, J;Spira, A;Fujimoto, J;Kadara, H;El-Hachem, N;Nemer, G;,
Front Oncol
,PubMed ID 30425966
[TBX2]
|
|
Tbx2 confers poor prognosis in glioblastoma and promotes temozolomide resistance with change of mitochondrial dynamics
,Yi, F;Du, J;Ni, W;Liu, W;,
Onco Targets Ther
,PubMed ID 28260920
[TBX2]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208558L1 | Lenti-ORF clone of TBX2 (Myc-DDK-tagged)-Human T-box 2 (TBX2) |
CNY 10,224.00 |
|
| RC208558L2 | Lenti-ORF clone of TBX2 (mGFP-tagged)-Human T-box 2 (TBX2) |
CNY 7,700.00 |
|
| RC208558L3 | Lenti-ORF clone of TBX2 (Myc-DDK-tagged)-Human T-box 2 (TBX2) |
CNY 10,224.00 |
|
| RC208558L4 | Lenti-ORF clone of TBX2 (mGFP-tagged)-Human T-box 2 (TBX2) |
CNY 10,224.00 |
|
| RG208558 | TBX2 (tGFP-tagged) - Human T-box 2 (TBX2) |
CNY 9,424.00 |
|
| SC125962 | TBX2 (untagged)-Human T-box 2 (TBX2) |
CNY 7,832.00 |
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