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Bcl11b (NM_021399) Mouse Tagged ORF Clone
CAT＃: MR210782
- TrueORF®
Bcl11b (Myc-DDK-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 2
ORF Plasmid: tGFP
"NM_021399" in other vectors (4)
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CNY 5,952.00
CNY 7,220.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 9130430L19Rik; AI604821; B630002E05Rik; BCL-11B; Ctip2; Rit1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR210782 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCCGCCGCAAACAGGGCAACCCGCAGCACTTGTCCCAGAGGGAACTCATCACGCCAGAGGCTGACC ATGTGGAGGCTACCATCCTCGAGGAAGACGAGGGTCTGGAGATAGAGGAGCCTAGCAGCCTGGGGCTGAT GGTGGGAGGCCCCGACCCTGATCTACTCACCTGTGGCCAGTGTCAGATGAACTTCCCGCTGGGGGACATC CTGGTTTTTATAGAGCACAAGAAGAAACAGTGTGGAGGCCTGGGCCCCTGCTACGACAAGGTCCTGGACA AGAGCAGTCCACCTCCCTCCTCTCGCTCTGAGCTCAGGAGAGTATCTGAGCCAGTGGAGATCGGGATCCA GGTCACCCCTGATGAAGATGACCACCTACTGTCACCCACGAAAGGCATCTGTCCCAAGCAGGAGAACATT GCAGGTAAAGATGAGCCTTCCAGCTACATTTGCACAACATGCAAGCAGCCCTTCAACAGCGCCTGGTTCC TGCTGCAGCACGCACAGAACACGCATGGCTTCCGAATCTACCTGGAGCCTGGGCCGGCCAGCACCTCGCT CACGCCCAGGCTCACCATCCCGCCACCGCTCGGGCCGGAGACCGTGGCGCAGTCCCCACTCATGAATTTC CTGGGGGACAGCAATCCTTTCAACCTGCTGCGCATGACGGGCCCCATCCTGCGGGACCACCCTGGCTTCG GTGAGGGCCGCTTGCCAGGTACGCCACCGCTCTTCAGCCCACCGCCACGCCATCACTTGGACCCACACCG CCTCAGTGCAGAGGAGATGGGGCTCGTGGCCCAGCACCCCAGTGCCTTCGACCGAGTCATGCGCCTGAAC CCCATGGCCATAGACTCTCCTGCCATGGACTTCTCCCGGCGGCTGCGAGAACTGGCCGGCAACAGCTCCA CGCCGCCGCCCGTGTCCCCAGGCCGTGGCAACCCTATGCACCGGCTGCTGAACCCTTTCCAGCCCAGTCC CAAGTCCCCGTTCCTCAGCACGCCACCGCTGCCACCCATGCCTGCGGGCACACCGCCACCGCAGCCGCCT GCCAAGAGCAAGTCCTGTGAGTTCTGCGGCAAGACCTTCAAGTTCCAGAGCAATCTCATCGTGCACCGGC GCAGCCACACGGGCGAGAAGCCCTACAAGTGCCAGCTGTGCGACCATGCGTGCTCGCAGGCGAGCAAGCT CAAGCGCCACATGAAGACGCACATGCACAAGGCGGGCTCTCTGGCTGGCCGCTCAGACGACGGGCTCTCA GCTGCCAGCTCCCCTGAGCCGGGCACCAGCGAGCTGCCAGGTGACCTGAAAGCGGCCGATGGCGACTTCC GCCACCATGAGAGCGACCCATCTCTGGGCCCCGAGCCTGAGGACGACGAGGACGAGGAGGAGGAAGAAGA GGAGCTGCTGCTGGAGAACGAGAGCCGGCCTGAGTCGAGCTTCAGCATGGACTCGGAGCTGGGCCGTGGC CGCGAGAACGGAGGTGGTGTGCCACCGGGGGTGGCGGGCGCAGGGGCTGCAGCTGCGGCTCTGGCGGATG AGAAGGCTCTGGCCCTGGGCAAGGTGATGGAGGACGCAGGGCTGGGCGCACTGCCGCAGTATGGGGAGAA GCGGGGCGCCTTCCTGAAGCGTGCAGGCGACACGGGTGATGCCGGAGCTGTTGGCTGTGGGGACGCGGGT GCACCGGGTGCAGTGAACGGGCGCGGCGGGGCCTTCGCGCCAGGCGCAGAGCCCTTTCCAGCTCTCTTCC CACGCAAGCCAGCACCGCTGCCCAGCCCTGGGCTCGGTGGTCCCGCGCTGCACGCGGCCAAGCGCATCAA GGTGGAGAAAGACCTGGAGCTGCCACCTGCCGCCCTCATCCCATCTGAGAACGTGTACTCGCAGTGGCTC GTGGGCTACGCAGCATCGCGCCACTTCATGAAGGACCCATTCCTGGGCTTCACGGATGCGCGCCAGTCGC CTTTCGCCACATCGTCGGAACATTCCTCTGAGAACGGCAGCCTGCGCTTCTCAACGCCACCCGGGGACCT GCTGGACGGCGGGCTGTCCGGGCGCAGTGGCACGGCGAGCGGGGGCAGCACACCTCACCTGGGTGGTCCG GGTCCTGGGAGGCCGAGCTCCAAGGAGGGCCGCCGCAGCGACACATGTGAGTACTGCGGCAAGGTCTTCA AGAACTGTAGCAACCTGACGGTGCACCGGAGGAGCCACACCGGCGAGCGGCCTTACAAGTGCGAGCTGTG CAACTACGCGTGTGCGCAGAGCAGCAAGCTCACGCGCCACATGAAGACGCACGGGCAGATCGGCAAGGAG GTGTACCGCTGCGACATCTGCCAGATGCCCTTCAGCGTCTACAGCACCCTGGAGAAACACATGAAAAAGT GGCACGGTGAACACTTGCTGACTAATGATGTCAAAATCGAGCAGGCTGAGAGGAGC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA >MR210782 protein sequence
Red=Cloning site Green=Tags(s) MSRRKQGNPQHLSQRELITPEADHVEATILEEDEGLEIEEPSSLGLMVGGPDPDLLTCGQCQMNFPLGDI LVFIEHKKKQCGGLGPCYDKVLDKSSPPPSSRSELRRVSEPVEIGIQVTPDEDDHLLSPTKGICPKQENI AGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEPGPASTSLTPRLTIPPPLGPETVAQSPLMNF LGDSNPFNLLRMTGPILRDHPGFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMRLN PMAIDSPAMDFSRRLRELAGNSSTPPPVSPGRGNPMHRLLNPFQPSPKSPFLSTPPLPPMPAGTPPPQPP AKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLS AASSPEPGTSELPGDLKAADGDFRHHESDPSLGPEPEDDEDEEEEEEELLLENESRPESSFSMDSELGRG RENGGGVPPGVAGAGAAAAALADEKALALGKVMEDAGLGALPQYGEKRGAFLKRAGDTGDAGAVGCGDAG APGAVNGRGGAFAPGAEPFPALFPRKPAPLPSPGLGGPALHAAKRIKVEKDLELPPAALIPSENVYSQWL VGYAASRHFMKDPFLGFTDARQSPFATSSEHSSENGSLRFSTPPGDLLDGGLSGRSGTASGGSTPHLGGP GPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKE VYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_021399 |
| ORF Size | 2439 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021399.2, NP_067374.2 |
| RefSeq Size | 7707 bp |
| RefSeq ORF | 2439 bp |
| Locus ID | 58208 |
| UniProt ID | Q99PV8 |
| MW | 87.3 kDa |
| Gene Summary | Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals (PubMed:12717433). Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (By similarity). Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes (PubMed:16809611). Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC201286 | Bcl11b (untagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 2, (10ug) |
CNY 2,000.00 |
|
| MG210782 | Bcl11b (tGFP-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 2 |
CNY 7,980.00 |
|
| MR210782L3 | Lenti ORF clone of Bcl11b (Myc-DDK-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 2 |
CNY 9,120.00 |
|
| MR210782L4 | Lenti ORF clone of Bcl11b (mGFP-tagged) - Mouse B-cell leukemia/lymphoma 11B (Bcl11b), transcript variant 2 |
CNY 8,352.00 |
