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Traf5 (NM_011633) Mouse Tagged ORF Clone
CAT＃: MR208836
- TrueORF®
Traf5 (Myc-DDK-tagged) - Mouse TNF receptor-associated factor 5 (Traf5)
"NM_011633" in other vectors (3)
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CNY 4,160.00
CNY 4,560.00
| Cited in 2 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR208836 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTCATTCGGAGGAGCAAGCGGCTGTCCCCTGCGCCTTCATCCGCCAGAACTCTGGCAACTCAATTT CCTTGGACTTTGAGCCCGACACCGAGTACCAGTTTGTGGAGCAGCTGGAAGAACGCTACAAATGTGCCTT CTGCCACTCCGTGCTTCACAACCCCCACCAGACCGGCTGCGGGCACCGCTTCTGCCAGCAGTGCATCCGG TCTCTGAGAGAATTGAACTCGGTGCCGATCTGCCCGGTAGACAAGGAGGTCATCAAGCCTCAGGAGGTGT TCAAAGACAACTGCTGCAAAAGAGAAGTTCTCAATTTACACGTCTACTGCAAAAACGCCCCCGGGTGCAA TGCCAGGATTATTCTGGGACGATTCCAGGACCACCTTCAGCACTGTTCCTTCCAAGCCGTGCCCTGCCCT AACGAGAGCTGCCGGGAAGCCATGCTCCGGAAAGACGTGAAAGAGCACCTGAGCGCATACTGCCGGTTCC GAGAGGAGAAGTGCCTTTACTGCAAAAGGGACATAGTGGTGACCAACCTGCAGGATCATGAGGAAAACTC GTGTCCTGCGTACCCAGTGTCTTGTCCCAACAGGTGTGTGCAGACTATTCCAAGAGCTAGGGTGAATGAA CACCTTACTGTATGTCCTGAGGCTGAGCAAGACTGTCCCTTTAAGCACTATGGCTGCACTGTCAAGGGTA AGCGGGGGAACTTGCTGGAGCATGAGCGGGCAGCCCTGCAGGACCACATGCTTCTGGTTTTAGAGAAGAA CTACCAACTAGAACAGCGGATCTCTGATTTATATCAGAGTCTCGAACAGAAGGAAAGCAAGATCCAGCAG CTGGCAGAAACCGTGAAGAAGTTCGAAAAGGAGCTTAAGCAGTTCACACAGATGTTTGGCAGAAATGGAA CTTTCCTCTCAAATGTCCAGGCTCTCACCAGTCACACGGACAAGTCAGCTTGGCTGGAAGCGCAGGTGCG GCAGCTGCTACAAATAGTTAACCAGCAGCCAAGTCGACTTGATCTGAGGTCTTTGGTGGATGCGGTTGAC AGCGTGAAACAGAGGATCACCCAGCTGGAAGCCAGTGACCAGAGATTAGTTCTTTTAGAGGGGGAGACCA GCAAGCACGACGCACACATTAATATCCACAAAGCACAGCTGAATAAGAACGAAGAGCGGTTTAAGCAGCT GGAGGGCGCCTGCTACAGTGGCAAGCTCATCTGGAAGGTGACAGATTACAGGGTGAAGAAGAGGGAGGCC GTGGAGGGGCACACAGTGTCCGTCTTCAGCCAGCCTTTCTACACCAGCCGCTGCGGCTACCGGCTCTGTG CCAGGGCGTACCTGAACGGGGACGGGTCGGGGAAGGGAACGCACCTGTCCCTGTACTTTGTGGTGATGCG CGGTGAGTTTGACTCGCTGCTGCAGTGGCCGTTCAGGCAGAGGGTGACCCTGATGCTTTTGGACCAGAGC GGCAAGAAGAACCATATTGTGGAGACCTTCAAAGCTGACCCCAACAGCAGCAGCTTCAAAAGGCCAGATG GCGAGATGAACATTGCCTCTGGCTGTCCCCGCTTTGTGTCGCACTCTACTCTGGAGAACTCCAAGAACAC CTACATTAAAGACGACACACTGTTCTTGAAAGTGGCCGTGGATTTAACTGACTTGGAGGATCTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR208836 protein sequence
Red=Cloning site Green=Tags(s) MAHSEEQAAVPCAFIRQNSGNSISLDFEPDTEYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIR SLRELNSVPICPVDKEVIKPQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCP NESCREAMLRKDVKEHLSAYCRFREEKCLYCKRDIVVTNLQDHEENSCPAYPVSCPNRCVQTIPRARVNE HLTVCPEAEQDCPFKHYGCTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQ LAETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVD SVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREA VEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQS GKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDLTDLEDL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_011633 |
| ORF Size | 1677 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_011633.2 |
| RefSeq Size | 2249 bp |
| RefSeq ORF | 1677 bp |
| Locus ID | 22033 |
| UniProt ID | P70191 |
| MW | 64.1 kDa |
| Gene Summary | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.[UniProtKB/Swiss-Prot Function] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
TNFR-Associated Factors 2 and 5 Differentially Regulate the Instructive IL-6 Receptor Signaling Required for Th17 Development
,Nagashima, H;Okuyama, Y;Hayashi, T;Ishii, N;So, T;,
J. Immunol.
,PubMed ID 27076680
[Traf5]
|
|
The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6
,Nagashima, H;Okuyama, Y;Asao, A;Kawabe, T;Yamaki, S;Nakano, H;Croft, M;Ishii, N;So, T;,
Nat. Immunol. 449-56 15 5. May 2014
,PubMed ID 24681564
[Traf5]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC200860 | Traf5 (untagged) - Mouse TNF receptor-associated factor 5 (Traf5), (10ug) |
CNY 2,000.00 |
|
| MR208836L3 | Lenti ORF clone of Traf5 (Myc-DDK-tagged) - Mouse TNF receptor-associated factor 5 (Traf5) |
CNY 6,460.00 |
|
| MR208836L4 | Lenti ORF clone of Traf5 (mGFP-tagged) - Mouse TNF receptor-associated factor 5 (Traf5) |
CNY 6,460.00 |
