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Myd88 (NM_010851) Mouse Untagged Clone
CAT＃: MC204847
Myd88 (untagged) - Mouse myeloid differentiation primary response gene 88 (Myd88), (10ug)
CNY 3,600.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC058787
CCCAGGGTTGCCTGCCATGTCTGCGGGAGACCCCCGCGTGGGATCCGGGTCCCTGGACTCCTTCATGTTC TCCATACCCTTGGTCGCGCTTAACGTGGGAGTGAGGCGCCGCCTATCGCTGTTCTTGAACCCTCGGACGC CCGTGGCGGCCGACTGGACCTTGCTGGCGGAGGAGATGGGCTTCGAGTACTTGGAGATCCGAGAGCTGGA AACGCGCCCTGACCCCACTCGCAGTTTGTTGGATGCCTGGCAGGGGCGCTCTGGCGCGTCTGTCGGCAGG CTGCTAGAGCTGCTGGCCTTGTTAGACCGTGAGGATATACTGAAGGAGCTGAAGTCGCGCATCGAGGAGG ACTGCCAGAAATACTTAGGTAAGCAGCAGAACCAGGAGTCCGAGAAGCCTTTACAGGTGGCCAGAGTGGA AAGCAGTGTCCCACAAACAAAGGAACTGGGAGGCATCACCACCCTTGATGACCCCCTAGGACAAACGCCG GAACTTTTCGATGCCTTTATCTGCTACTGCCCCAACGATATCGAGTTTGTGCAGGAGATGATCCGGCAAC TAGAACAGACAGACTATCGGCTTAAGTTGTGTGTGTCCGACCGTGACGTCCTGCCGGGCACCTGTGTCTG GTCCATTGCCAGCGAGCTAATTGAGAAAAGGTGTCGCCGCATGGTGGTGGTTGTTTCTGACGATTATCTA CAGAGCAAGGAATGTGACTTCCAGACCAAGTTTGCACTCAGCCTGTCTCCAGGTGTCCAACAGAAGCGAC TGATTCCTATTAAATACAAGGCGATGAAGAAGGACTTTCCCAGTATCCTGCGGTTCATCACTATATGCGA CTATACCAACCCTTGCACCAAGTCCTGGTTCTGGACCCGCCTTGCCAAGGCTTTGTCCCTGCCCTGAAGA TGACCCTGGGAGCCCTAGGGCAGAGGGGAAGATGAGACTGATGCGGAGCCAGATTCTCTGATGCCGTCCT GTCTACATCTTTGACTCCCCTGGGCTCAACCCGTGTTCAATGATGACTGGCCTGAGCAACTAGGACTGCC TTTCCTCCCAGCCACCCATGCCTGTGCACGCACCTCAGTACACACATGCCTCCTCGCACACACAGGCATC TGCATATGTGTGTTTCCTTTGGGACAGCTCCCAAGGATAGCTGAGTGGAAGAGTTCTATCATCAAGGGGG CCTGGCCATCTCCCTGGACAAAAGTGGGGTGCCTTTGCTACAGGTAGTGGCACGGGCCTATAGTTTCAGC ATTTGGGAGGTAGAGGCAGGAGAATCAGGAGTTCAAGCTTATCCTTGGCAACACACCTAGTTTAAGGTCA GCCTGGGCTACATGAGAGCCTACCTCCCCCATCCCCTACCCCCAGAAAAGAAGGAAAATCTGGGGGCACT GTGGATTTCTCCTCTCTTTTCTCTACCTGTTGAAAGCAAAGTCTAGGAAGGCCCCAAACATGATAGCATT TGGGCCCTTAGTAAGCTGAAGATAAAAAGGAGAAGCTGTTTGGCTTCGCCCCACAAAGCAGCTGCAGGCT CAGCTGTTTTCTCCCCAGCAGCGAGGTTTGCATCTTCTTATTCCTTTCACGTTCTCTACCATAGAGGCAA TGTCATGGTCCCTCTCAGGGTACACCCCAGGGCCCTGAGTCCCCAAGAAAGTGAGTCTCCCCTCAGTGTC TGGGGGAGGAATGAGGCCTCTGTGCACGGTCTCATGGGGCATTTCACTGCTTGATGTTGAGCATTTTAAA GCAACCTGGGTCAAGTGTAAACCTCCTCCACCTGTGTTAGAGGTTTCATGGGAATGTCAATAAAGAAAAG AAGGGCTCGTGTTTGTACTTTGTACTTCTGTGTGTGAATTTATAATAAAAAGTATTCTATTTTGAGAAAG TGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_010851 |
| Insert Size | 891 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC058787, AAH58787 |
| RefSeq Size | 1922 bp |
| RefSeq ORF | 891 bp |
| Locus ID | 17874 |
| UniProt ID | P22366 |
| Gene Summary | Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (PubMed:9697844). Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:9575168, PubMed:9697844). Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway (PubMed:9697844). Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS) (PubMed:11909531). Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (PubMed:17018642). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (PubMed:17635956, PubMed:21998396). Mediates leukocyte recruitment at the inflammatory site (PubMed:18941239).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A Long Noncoding RNA, CHRF Regulates Cardiac Hypertrophy by Targeting miR-489
,Wang, K;Liu, F;Zhou, LY;Long, B;Yuan, SM;Wang, Y;Liu, CY;Sun, T;Zhang, XJ;Li, PF;,
Circ. Res., Feb 2014.
,PubMed ID 24557880
[Myd88]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227105 | Myd88 (tGFP-tagged) - Mouse myeloid differentiation primary response gene 88 (Myd88), (10ug) |
CNY 4,370.00 |
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| MR227105 | Myd88 (Myc-DDK-tagged) - Mouse myeloid differentiation primary response gene 88 (Myd88) |
CNY 3,600.00 |
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| MR227105L3 | Lenti ORF clone of Myd88 (Myc-DDK-tagged) - Mouse myeloid differentiation primary response gene 88 (Myd88) |
CNY 5,890.00 |
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| MR227105L4 | Lenti ORF clone of Myd88 (mGFP-tagged) - Mouse myeloid differentiation primary response gene 88 (Myd88) |
CNY 6,000.00 |
