GNG7 Mouse Monoclonal Antibody [Clone ID: OTI3G1]

Specifications

Product Data
Clone Name	OTI3G1
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 2-65 of human GNG7(NP_443079) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	7.3 kDa
Gene Name	G protein subunit gamma 7
Database Link	NP_443079 Entrez Gene 2788 Human UniProt ID O60262
Background	Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. [UniProtKB/Swiss-Prot Function]
Synonyms	FLJ00058
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Chemokine signaling pathway

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