CD38 Rabbit Monoclonal Antibody [Clone ID: HB7]

Specifications

Product Data
Clone Name	HB7
Applications	FC, WB
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Viable cells (1 x 10E7) of the human cell line, BJAB (Human Burkitt lymphoma B cell line), which was were injected intraperitoneally into 8-week-old BALB/c mice.
Specificity	This antibody binds to an epitope between amino acids 273-285 of human CD38, an approximately 45 kDa type II transmembrane protein, expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. Also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. Bimodally expressed during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. This antibody competes with clone AT13/5 (Ab00289) (Ellis 1995). A customer reports successfully using this antibody (coupled to magnetic beads) for isolation of plasma cells from the intestinal lamina propria.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD38 molecule
Database Link	Entrez Gene 952 Human UniProt ID P28907
Synonyms	T10
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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