CD71 (TFRC) Mouse Monoclonal Antibody [Clone ID: MEM-189]

CAT#: SM3037P

CD71 (TFRC) mouse monoclonal antibody, clone MEM-189, Purified



Need it in bulk or conjugated?
Get a free quote

CNY 3,140.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name MEM-189
Applications FC, IP, WB
Recommend Dilution Flow Cytometry: 2 µg/ml.
Immunoprecipitation.
Western Blot (Non Reducing Conditions).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen KG1 human acute myelogenous leukaemia cell line
Specificity This antibody reacts with CD71 antigen (transferrin receptor), a 95 kDa type II homodimeric transmembrane glycoprotein expressed on activated B and lymphocytes, macrophages and erythroid precursors; it is lost on resting blood leukocytes.
It does not block binding of transferrin to the receptor.
Formulation TBS buffer pH 8.0
State: Purified
State: Liquid purified IgG fraction (> 95% by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name transferrin receptor
Background CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
Synonyms TfR1, p90, Transferrin receptor protein 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...