Annexin A3 (ANXA3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/500-1/5000. Immunohistochemistry: 1/200-1/5000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from internal part of Human Annexin A3.
Specificity	Reacts with Human Annexin A3 . May cross react with protein from Primates due to sequence homology.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized powder Preservative: None
Reconstitution Method	Restore in distilled water
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibody at 2-4°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	annexin A3
Database Link	Entrez Gene 306 Human UniProt ID P12429
Background	The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-α calcimedin or ANX3, belongs to the Annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.
Synonyms	ANX3, Annexin-3, Annexin III, PAP-III, Lipocortin III, 35-alpha calcimedin
Reference Data

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