COTL1 Mouse Monoclonal Antibody [Clone ID: 5C8]

Specifications

Product Data
Clone Name	5C8
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/10000.  Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of Human COTL1 expressed in E. Coli.
Specificity	Recognizes Coactosin-like protein (COLT1).
Formulation	PBS State: Purified State: Liquid purified antibody Stabilizer: 0.5% protein stabilizer Preservative: 0.05% Sodium Azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	16 kDa
Gene Name	coactosin like F-actin binding protein 1
Database Link	Entrez Gene 23406 Human UniProt ID Q14019
Background	This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
Synonyms	COTL1, CLP
Note	Tissue Array Results Colon cancer, Rectal cancer, Hepatic Carcinoma, Liver cancer, Renal cell Carcinoma, Kidney, Prostate cancer, Lung cancer, Breast cancer, Ovarian cancer, Endometrial cancer, Cervical cancer, Bladder cancer, Myocardial.
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.