Interleukin-33 (IL33) (109-266, His-tag) Mouse Protein
CAT#: AR51680PU-N
Interleukin-33 (IL33) (109-266, His-tag) mouse recombinant protein, 0.25 mg
Size: 50 ug
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CNY 17,930.00
货期*
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规格
Specifications
Product Data | |
Species | Mouse |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSSIQGTSL LTQSPASLST YNDQSVSFVL ENGCYVINVD DSGKDQEQDQ VLLRYYESPC PASQSGDGVD GKKLMVNMSP IKDTDIWLHA NDKDYSVELQ RGDVSPPEQA FFVLHKKSSD FVSFECKNLP GTYIGVKDNQ LALVEEKDES CNNIMFKLSK I
|
Tag | His-tag |
Predicted MW | 18.1 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate buffered saline, 10% glycerol, 1 mM DTT |
Preparation | Liquid purified protein |
Protein Description | Recombinant mouse IL33 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Endotoxin | < 1.0 EU per 1 μg of protein (determined by LAL method) |
Reference Data | |
RefSeq | NP_001158196 |
Locus ID | 77125 |
UniProt ID | Q8BVZ5 |
Cytogenetics | 19 C1 |
Synonyms | 9230117N10Rik; Il-33; Il1f11; NF-HEV |
Summary | Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury.[UniProtKB/Swiss-Prot Function] |
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