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GRK2 (NM_001619) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC210327L3V
- LentiORF®
-
Lenti ORF particles, ADRBK1 (Myc-DDK tagged) - Human adrenergic, beta, receptor kinase 1 (ADRBK1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
| Product Data | |
| Product Name | GRK2 (NM_001619) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ADRBK1; BARK1; BETA-ARK1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001619 |
| ORF Size | 2076 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC210327).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001619.2 |
| RefSeq Size | 3603 bp |
| RefSeq ORF | 2070 bp |
| Locus ID | 156 |
| Domains | RGS, pkinase, S_TK_X, TyrKc, PH, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway, Endocytosis |
| MW | 79.4 kDa |
| Gene Summary | This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease. [provided by RefSeq, Sep 2017] |
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