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MVK (NM_000431) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC201971L3V
- LentiORF®
-
Lenti ORF particles, MVK (Myc-DDK tagged) - Human mevalonate kinase (MVK), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
| Product Data | |
| Product Name | MVK (NM_000431) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | LRBP; MK; MVLK; POROK3 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_000431 |
| ORF Size | 1188 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201971).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000431.1 |
| RefSeq Size | 2084 bp |
| RefSeq ORF | 1191 bp |
| Locus ID | 4598 |
| Domains | GHMP_kinases |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
| MW | 42.5 kDa |
| Gene Summary | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Documents
| Product Manuals |
| FAQs |
| SDS |
