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Six1 (NM_009189) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR203850L4V
- LentiORF®
-
Lenti ORF particles, Six1 (GFP-tagged) - Mouse sine oculis-related homeobox 1 homolog (Drosophila) (Six1), 200ul, >10^7 TU/mL
Mouse Protein / Lysate Request
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Six1 (NM_009189) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | BB138287 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_009189 |
| ORF Size | 852 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR203850).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009189.1 |
| RefSeq Size | 2601 bp |
| RefSeq ORF | 855 bp |
| Locus ID | 20471 |
| Gene Summary | Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCNA1, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2.[UniProtKB/Swiss-Prot Function] |
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