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Sumo1 (NM_009460) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR200317L3V
- LentiORF®
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Lenti ORF particles, Sumo1 (Myc-DDK-tagged) - Mouse SMT3 suppressor of mif two 3 homolog 1 (yeast) (Sumo1), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Sumo1 (NM_009460) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | GMP1; PIC1; SENTRIN; SMT3; Smt3C; SMT3H3; SMTP3; SUMO-1; Ubl1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_009460 |
| ORF Size | 306 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR200317).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009460.2, NP_033486.1 |
| RefSeq Size | 1230 bp |
| RefSeq ORF | 306 bp |
| Locus ID | 22218 |
| Gene Summary | Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (By similarity).[UniProtKB/Swiss-Prot Function] |
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