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APEX2 (NM_014481) Human Untagged Clone
CAT＃: SC122813
APEX2 (untagged)-Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APE2; APEXL2; XTH2; ZGRF2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_014481 edited
AGGTTGGCGCGGGCTGGGAGGTGTTCCAGCCCTTTAAGATGTTGCGCGTGGTGAGCTGGA ACATCAATGGGATTCGGAGACCCCTGCAAGGGGTGGCAAATCAGGAACCCAGCAACTGTG CCGCCGTGGCCGTGGGGCGCATTTTGGACGAGCTGGATGCGGATATCGTCTGTCTCCAGG AAACCAAAGTGACCAGGGATGCACTGACAGAGCCCCTGGCTATCGTTGAGGGTTATAACT CCTATTTCAGCTTCAGCCGCAACCGTAGCGGCTATTCTGGTGTAGCCACCTTCTGTAAGG ACAATGCTACCCCAGTGGCTGCTGAAGAAGGCCTGAGTGGCCTGTTTGCCACCCAGAATG GGGATGTTGGTTGCTATGGAAACATGGATGAGTTTACCCAAGAGGAACTCCGGGCTCTGG ATAGTGAGGGCAGGGCCCTCCTCACACAGCATAAGATCCGCACATGGGAAGGTAAGGAGA AGACCTTGACCCTAATCAACGTGTACTGCCCCCATGCGGACCCTGGGAGGCCTGAGCGGC TAGTCTTTAAGATGCGCTTCTATCGTTTGCTGCAAATCCGAGCAGAAGCCCTCCTGGCGG CAGGCAGCCATGTGATCATTCTGGGTGACCTGAATACAGCCCACCGCCCCATTGACCACT GGGATGCAGTCAACCTGGAATGCTTTGAAGAGGACCCAGGGCGCAAGTGGATGGACAGCT TGCTCAGTAACTTGGGGTGCCAGTCTGCCTCTCATGTAGGGCCCTTCATCGATAGCTACC GCTGCTTCCAACCAAAGCAGGAGGGGGCCTTCACCTGCTGGTCAGCAGTCACTGGCGCCC GCCATCTCAACTATGGCTCCCGGCTTGACTATGTGCTGGGGGACAGGACCCTGGTCATAG ACACCTTTCAGGCCTCTTTCCTGCTGCCTGAGGTGATGGGCTCTGACCACTGCCCTGTGG GTGCAGTCTTGAGTGTGTCCTCTGTGCCTGCAAAACAGTGCCCACCTCTGTGCACCCGCT TCCTCCCTGAGTTTGCAGGCACCCAGCTCAAGATCCTTCGCTTCCTAGTTCCTCTCGAAC AAAGTCCTGTGTTGGAGCAGTCGACGCTGCAGCACAACAATCAAACCCGGGTACAGACAT GCCAAAACAAAGCCCAAGTGCGCTCAACCAGGCCTCAGCCCAGTCAGGTTGGCTCTAGCA GAGGCCAGAAAAACCTGAAGAGCTACTTTCAGCCCTCCCCTAGCTGTCCCCAAGCCTCTC CTGACATAGAGCTGCCTAGCCTACCACTGATGAGCGCCCTCATGACCCCGAAGACTCCAG AAGAGAAGGCAGTGGCCAAAGTGGTGAAGGGGCAGGCCAAGACTTCAGAAGCCAAAGATG AGAAGGAGTTACGGACCTCATTCTGGAAGTCTGTGCTGGCGGGGCCCTTGCGCACACCCC TCTGTGGGGGCCACAGGGAGCCATGTGTGATGCGTACTGTGAAGAAGCCAGGACCCAACT TGGGCCGCCGCTTCTACATGTGTGCCAGGCCCCGGGGTCCTCCCACTGACCCCTCCTCCC GGTGCAACTTCTTCCTCTGGAGCAGGCCCAGCTGAACCAATGGAGGCCTGGGGACATCTG GCATGGTCACCCCTGCACATGATCTGAGGCCAGCTCCCCTTCCCTGAGCTGCCTCCTGCT TCTCCCTCAAAGTCTCCTACCCTTCTCTTCCTCTTTTAAGCCCTCTCTTCCTCGCTTTCC TTCCTACCTAGCTCCTTGTTGGTGAGCTTCTTGTGCCTTAATCCTGTGACCCAGCCCCTT ACACCACTTTCCACCTTCCTGTCCGAAGTACACGGACACTAGCTGCCCCAGGAAGTTGTG TGATTTTAAATCACTTCTGTCTTTGCTGGAAAGTGTATTTGTGCATAAATAAAGTCTGTG TATTTGTTTCAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_014481 unedited
NAACGTCGAAATTGTAAACGCCTCCTATAGGCGGCCGCGACATTCGCACGAGGAGGTTGG CGCGGGCTGGGAGGTGTTCCAGCCCTTTAAGAGTTGCGCGTGGTGAGCTGGAACATCAAT GGGATTCGGAGACCCCTGCAAGGGGTGGCAAATCAGGAACCCAGCAACTGTGCCGCCGTG GCCGTGGGGCGCATTTTGGACGAGCTGGATGCGGATATCGTCTGTCTCCAGGAAACCAAA GTGACCAGGGATGCACTGACAGAGCCCCTGGCTATCGTTGAGGGTTATAACTCCTATTTC AGCTTCAGCCGCAACCGTAGCGGCTATTCTGGTGTAGCCACCTTCTGTAAGGACAATGCT ACCCCAGTGGCTGCTGAAGAAGGCCTGAGTGGCCTGTTTGCCACCCAGAATGGGGATGTT GGTTGCTATGGAAACATGGATGAGTTTACCCAAGAGGAACTCCGGGCTCTGGATAGTGAG GGCAGGGCCCTCCTCACACAGCATAAGATCCGCACATGGGAAGGTAAGGAGAAGACCTTG ACCCTAATCAACGTGTACTGCCCCCATGCGGACCCTGGGAGGCCTGAGCGGCTAGTCTTT AAGATGCGCTTCTATCGTTTGCTGCAAATCCGAGCAGAAGCCCTCCTGGCGGCAGGCAGC CATGTGATCATTCTGGGTGACCTGAATACAGCCCACCGCCCCATTGACCACTGGGATGCA GTCAACCTGGAATGCTTTGAAGAGGACCCAGGGCGCAAGTGGATGGACAGCTTGCTCAGT AACTTGGGGTGGCAGTCTGCCTCTCATGTAGGGCCCTTCATCGATAGCTACCGCTGCTTC CAACCAAAGCAGGAGGGGGCCTTCACCTGCTGGTCAGCAGTCACTGGCGCCCGCCATCTC ACTATGGCTCCCGGCTTGACTATGTGCTGGGGGGACAGA |
| Restriction Sites | Please inquire |
| ACCN | NM_014481 |
| Insert Size | 1953 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014481.2, NP_055296.2 |
| RefSeq Size | 1991 bp |
| RefSeq ORF | 1557 bp |
| Locus ID | 27301 |
| UniProt ID | Q9UBZ4 |
| Protein Families | Druggable Genome |
| Protein Pathways | Base excision repair |
| Gene Summary | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200320 | APEX2 (Myc-DDK-tagged)-Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein |
CNY 3,856.00 |
|
| RC200320L1 | Lenti ORF clone of Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200320L2 | Lenti ORF clone of Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
| RC200320L3 | Lenti ORF clone of Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200320L4 | Lenti ORF clone of Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
| RG200320 | APEX2 (tGFP-tagged) - Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein |
CNY 4,370.00 |
