Ciapin1 (NM_001007689) Rat Tagged Lenti ORF Clone
CAT#: RR214471L4
- LentiORF®
Lenti ORF clone of Ciapin1 (mGFP-tagged ORF) - Rat cytokine induced apoptosis inhibitor 1 (Ciapin1), (10 ug)
"NM_001007689" in other vectors (3)
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CNY 6,650.00
Cited in 1 publication. |
Specifications
Product Data | |
Type | Rat Tagged ORF Clone |
Tag | mGFP |
Synonyms | MGC94686 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR214471).
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Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001007689 |
ORF Size | 927 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001007689.1, NP_001007690.1 |
RefSeq Size | 1806 bp |
RefSeq ORF | 930 bp |
Locus ID | 307649 |
UniProt ID | Q5XID1 |
Gene Summary | Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Cytokine‐induced apoptosis inhibitor 1 (CIAPIN1) accelerates vascular remodelling via p53 and JAK2‐STAT3 regulation in vascular smooth muscle cells
,null,
British Journal of Pharmacology
,PubMed ID 34289085
[Ciapin1]
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Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RN214471 | Ciapin1 (untagged ORF) - Rat cytokine induced apoptosis inhibitor 1 (Ciapin1), (10 ug) |
CNY 3,990.00 |
|
RR214471 | Ciapin1 (Myc-DDK-tagged ORF) - Rat cytokine induced apoptosis inhibitor 1 (Ciapin1), (10 ug) |
CNY 2,640.00 |
|
RR214471L3 | Lenti ORF clone of Ciapin1 (Myc-DDK-tagged ORF) - Rat cytokine induced apoptosis inhibitor 1 (Ciapin1), (10 ug) |
CNY 6,080.00 |
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