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RTEL1 (NM_032957) Human Tagged ORF Clone
CAT＃: RC221988
RTEL1 (Myc-DDK-tagged)-Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2
ORF Plasmid: tGFP
"NM_032957" in other vectors (6)
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CNY 13,576.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC221988 representing NM_032957
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCCAAGATAGTCCTGAATGGTGTGACCGTAGACTTCCCTTTCCAGCCCTACAAATGCCAACAGGAGT ACATGACCAAGGTCCTGGAATGTCTGCAGCAGAAGGTGAATGGCATCCTGGAGAGCCCTACGGGTACAGG GAAGACGCTGTGCCTGCTGTGCACCACGCTGGCCTGGCGAGAACACCTCCGAGACGGCATCTCTGCCCGC AAGATTGCCGAGAGGGCGCAAGGAGAGCTTTTCCCGGATCGGGCCTTGTCATCCTGGGGCAACGCTGCTG CTGCTGCTGGAGACCCCATAGCTTGCTACACGGACATCCCAAAGATTATTTACGCCTCCAGGACCCACTC GCAACTCACACAGGTCATCAACGAGCTTCGGAACACCTCCTACCGGCCTAAGGTGTGTGTGCTGGGCTCC CGGGAGCAGCTGTGCATCCATCCTGAGGTGAAGAAACAAGAGAGTAACCATCTACAGATCCACTTGTGCC GTAAGAAGGTGGCAAGTCGCTCCTGTCATTTCTACAACAACGTAGAAGAAAAAAGCCTGGAGCAGGAGCT GGCCAGCCCCATCCTGGACATTGAGGACTTGGTCAAGAGCGGAAGCAAGCACAGGGTGTGCCCTTACTAC CTGTCCCGGAACCTGAAGCAGCAAGCCGACATCATATTCATGCCGTACAATTACTTGTTGGATGCCAAGA GCCGCAGAGCACACAACATTGACCTGAAGGGGACAGTCGTGATCTTTGACGAAGCTCACAACGTGGAGAA GATGTGTGAAGAATCGGCATCCTTTGACCTGACTCCCCATGACCTGGCTTCAGGACTGGACGTCATAGAC CAGGTGCTGGAGGAGCAGACCAAGGCAGCGCAGCAGGGTGAGCCCCACCCGGAGTTCAGCGCGGACTCCC CCAGCCCAGGGCTGAACATGGAGCTGGAAGACATTGCAAAGCTGAAGATGATCCTGCTGCGCCTGGAGGG GGCCATCGATGCTGTTGAGCTGCCTGGAGACGACAGCGGTGTCACCAAGCCAGGGAGCTACATCTTTGAG CTGTTTGCTGAAGCCCAGATCACGTTTCAGACCAAGGGCTGCATCCTGGACTCGCTGGACCAGATCATCC AGCACCTGGCAGGACGTGCTGGAGTGTTCACCAACACGGCCGGACTGCAGAAGCTGGCGGACATTATCCA GATTGTGTTCAGTGTGGACCCCTCCGAGGGCAGCCCTGGTTCCCCAGCAGGGCTGGGGGCCTTACAGTCC TATAAGGTGCACATCCATCCTGATGCTGGTCACCGGAGGACGGCTCAGCGGTCTGATGCCTGGAGCACCA CTGCAGCCAGAAAGCGAGGGAAGGTGCTGAGCTACTGGTGCTTCAGTCCCGGCCACAGCATGCACGAGCT GGTCCGCCAGGGCGTCCGCTCCCTCATCCTTACCAGCGGCACGCTGGCCCCGGTGTCCTCCTTTGCTCTG GAGATGCAGATCCCTTTCCCAGTCTGCCTGGAGAACCCACACATCATCGACAAGCACCAGATCTGGGTGG GGGTCGTCCCCAGAGGCCCCGATGGAGCCCAGTTGAGCTCCGCGTTTGACAGACGGTTTTCCGAGGAGTG CTTATCCTCCCTGGGGAAGGCTCTGGGCAACATCGCCCGCGTGGTGCCCTATGGGCTCCTGATCTTCTTC CCTTCCTATCCTGTCATGGAGAAGAGCCTGGAGTTCTGGCGGGCCCGCGACTTGGCCAGGAAGATGGAGG CGCTGAAGCCGCTGTTTGTGGAGCCCAGGAGCAAAGGCAGCTTCTCCGAGACCATCAGTGCTTACTATGC AAGGGTTGCCGCCCCTGGGTCCACCGGCGCCACCTTCCTGGCGGTCTGCCGGGGCAAGGCCAGCGAGGGG CTGGACTTCTCAGACACGAATGGCCGTGGTGTGATTGTCACGGGCCTCCCGTACCCCCCACGCATGGACC CCCGGGTTGTCCTCAAGATGCAGTTCCTGGATGAGATGAAGGGCCAGGGTGGGGCTGGGGGCCAGTTCCT CTCTGGGCAGGAGTGGTACCGGCAGCAGGCGTCCAGGGCTGTGAACCAGGCCATCGGGCGAGTGATCCGG CACCGCCAGGACTACGGAGCTGTCTTCCTCTGTGACCACAGGTTCGCCTTTGCCGACGCAAGAGCCCAAC TGCCCTCCTGGGTGCGTCCCCACGTCAGGGTGTATGACAACTTTGGCCATGTCATCCGAGACGTGGCCCA GTTCTTCCGTGTTGCCGAGCGAACTATGCCAGCGCCGGCCCCCCGGGCTACAGCACCCAGTGTGCGTGGA GAAGATGCTGTCAGCGAGGCCAAGTCGCCTGGCCCCTTCTTCTCCACCAGGAAAGCTAAGAGTCTGGACC TGCATGTCCCCAGCCTGAAGCAGAGGTCCTCAGGGTCACCAGCTGCCGGGGACCCCGAGAGTAGCCTGTG TGTGGAGTATGAGCAGGAGCCAGTTCCTGCCCGGCAGAGGCCCAGGGGGCTGCTGGCCGCCCTGGAGCAC AGCGAACAGCGGGCGGGGAGCCCTGGCGAGGAGCAGGCCCACAGCTGCTCCACCCTGTCCCTCCTGTCTG AGAAGAGGCCGGCAGAAGAACCGCGAGGAGGGAGGAAGAAGATCCGGCTGGTCAGCCACCCGGAGGAGCC CGTGGCTGGTGCACAGACGGACAGGGCCAAGCTCTTCATGGTGGCCGTGAAGCAGGAGTTGAGCCAAGCC AACTTTGCCACCTTCACCCAGGCCCTGCAGGACTACAAGGGTTCCGATGACTTCGCCGCCCTGGCCGCCT GTCTCGGCCCCCTCTTTGCTGAGGACCCCAAGAAGCACAACCTGCTCCAAGGCTTCTACCAGTTTGTGCG GCCCCACCATAAGCAGCAGTTTGAGGAGGTCTGTATCCAGCTGACAGGACGAGGCTGTGGCTATCGGCCT GAGCACAGCATTCCCCGAAGGCAGCGGGCACAGCCGGTCCTGGACCCCACTGGAAGAACGGCGCCGGATC CCAAGCTGACCGTGTCCACGGCTGCAGCCCAGCAGCTGGACCCCCAAGAGCACCTGAACCAGGGCAGGCC CCACCTGTCGCCCAGGCCACCCCCAACAGGAGACCCTGGCAGCCAACCACAGTGGGGGTCTGGAGTGCCC AGAGCAGGGAAGCAGGGCCAGCACGCCGTGAGCGCCTACCTGGCTGATGCCCGCAGGGCCCTGGGGTCCG CGGGCTGTAGCCAACTCTTGGCAGCGCTGACAGCCTATAAGCAAGACGACGACCTCGACAAGGTGCTGGC TGTGTTGGCCGCCCTGACCACTGCAAAGCCAGAGGACTTCCCCCTGCTGCACAGGTTCAGCATGTTTGTG CGTCCACACCACAAGCAGCGCTTCTCACAGACGTGCACAGACCTGACCGGCCGGCCCTACCCGGGCATGG AGCCACCGGGACCCCAGGAGGAGAGGCTTGCCGTGCCTCCTGTGCTTACCCACAGGGCTCCCCAACCAGG CCCCTCACGGTCCGAGAAGACCGGGAAGACCCAGAGCAAGATCTCGTCCTTCCTTAGACAGAGGCCAGCA GGGACTGTGGGGGCGGGCGGTGAGGATGCAGGTCCCAGCCAGTCCTCAGGACCTCCCCACGGGCCTGCAG CATCTGAGTGGGGTGAGCCTCATGGGAGAGACATCGCTGGGCAGCAGGCCACGGGAGCTCCGGGCGGGCC CCTCTCAGCAGGCTGTGTGTGCCAGGGCTGTGGGGCAGAGGACGTGGTGCCCTTCCAGTGCCCTGCCTGT GACTTCCAGCGCTGCCAAGCCTGCTGGCAACGGCACCTTCAGGCCTCTAGGATGTGCCCAGCCTGCCACA CCGCCTCCAGGAAGCAGAGCGTCATGCAGGTCTTCTGGCCAGAGCCCCAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC221988 representing NM_032957
Red=Cloning site Green=Tags(s) MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISAR KIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKVCVLGS REQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYY LSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDVID QVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFE LFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAGLGALQS YKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFAL EMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLIFF PSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEG LDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIR HRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVRG EDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPARQRPRGLLAALEH SEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLFMVAVKQELSQA NFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRP EHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPPTGDPGSQPQWGSGVP RAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFV RPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEKTGKTQSKISSFLRQRPA GTVGAGGEDAGPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGCVCQGCGAEDVVPFQCPAC DFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_032957 |
| ORF Size | 3900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_032957.3, NP_116575.2 |
| RefSeq Size | 4651 bp |
| RefSeq ORF | 3732 bp |
| Locus ID | 51750 |
| UniProt ID | Q9NZ71 |
| Protein Families | Druggable Genome |
| MW | 142.8 kDa |
| Gene Summary | This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221988L1 | Lenti ORF clone of Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, Myc-DDK-tagged |
CNY 15,976.00 |
|
| RC221988L2 | Lenti ORF clone of Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mGFP tagged |
CNY 15,580.00 |
|
| RC221988L3 | Lenti ORF clone of Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, Myc-DDK-tagged |
CNY 15,580.00 |
|
| RC221988L4 | Lenti ORF clone of Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2, mGFP tagged |
CNY 15,580.00 |
|
| RG221988 | RTEL1 (tGFP-tagged) - Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2 |
CNY 15,176.00 |
|
| SC309730 | RTEL1 (untagged)-Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 2 |
CNY 25,080.00 |
