SCARF2 (NM_182895) Human Tagged ORF Clone

Specifications

Product Data
Type	Human Tagged ORF Clone
Tag	Myc-DDK
Synonyms	NSR1; SREC-II; SREC2; SRECRP-1; VDEGS
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >RC212667 representing NM_182895 Red=Cloning site Blue=ORF Green=Tags(s) CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC GCCC ATGGAGGGCGCAGGGCCCCGGGGGGCCGGGCCGGCGCGGCGCCGGGGAGCCGGGGGGCCGCCGTCACCGC TGCTGCCGTCGCTGCTGCTGCTGCTGCTGCTCTGGATGCTGCCGGACACCGTGGCGCCTCAGGAACTGAA CCCTCGCGGCCGCAACGTGTGCCGTGCTCCCGGCTCCCAGGTGCCCACGTGCTGCGCTGGCTGGAGGCAG CAAGGGGACGAGTGTGGGATTGCGGTGTGCGAAGGCAACTCCACGTGCTCAGAGAACGAGGTGTGCGTGA GGCCTGGCGAGTGCCGCTGCCGCCACGGCTACTTCGGTGCCAACTGCGACACCAAGTGCCCGCGCCAGTT CTGGGGCCCCGACTGCAAGGAGCTGTGTAGCTGCCACCCACACGGGCAGTGCGAGGACGTGACAGGCCAG TGTACTTGTCACGCGCGGCGCTGGGGCGCGCGCTGCGAGCATGCGTGCCAGTGCCAGCACGGCACGTGCC ACCCGCGGAGCGGCGCGTGCCGCTGTGAGCCCGGCTGGTGGGGCGCGCAGTGCGCCAGCGCGTGCTACTG CAGCGCCACGTCGCGCTGCGACCCACAGACCGGCGCCTGCCTGTGCCACGCAGGCTGGTGGGGCCGCAGC TGCAACAACCAGTGCGCCTGCAACTCGTCTCCCTGCGAGCAGCAGAGCGGCCGCTGTCAGTGCCGCGAGC GTACGTTCGGCGCGCGCTGCGATCGCTACTGCCAGTGCTTCCGCGGCCGCTGCCACCCTGTGGACGGCAC GTGTGCCTGCGAGCCGGGCTACCGCGGCAAGTACTGTCGCGAGCCGTGCCCCGCCGGCTTCTACGGCTTG GGCTGTCGCCGCCGGTGTGGCCAGTGCAAGGGCCAGCAGCCGTGCACGGTGGCCGAGGGCCGCTGCTTGA CGTGCGAGCCCGGCTGGAACGGAACCAAGTGCGACCAGCCTTGCGCCACCGGTTTCTATGGCGAGGGCTG CAGCCACCGCTGTCCGCCATGCCGCGACGGGCATGCCTGTAACCATGTCACCGGCAAGTGTACGCGCTGC AACGCGGGCTGGATCGGCGACCGGTGCGAGACCAAGTGTAGCAATGGCACTTACGGCGAGGACTGCGCCT TCGTGTGCGCCGACTGCGGCAGCGGACACTGCGACTTCCAGTCGGGGCGCTGCCTGTGCAGCCCTGGCGT CCACGGGCCCCACTGTAACGTGACGTGCCCGCCCGGACTCCACGGCGCGGACTGTGCTCAGGCCTGCAGC TGCCACGAGGACACGTGCGACCCGGTCACTGGTGCCTGCCACCTAGAAACCAACCAGCGCAAGGGCGTGA TGGGCGCGGGCGCGCTGCTCGTCCTGCTCGTCTGCCTGCTGCTCTCGCTGCTCGGCTGCTGCTGCGCTTG CCGCGGCAAGGACCCTACGCGCCGGGAGCTTTCGCTTGGGAGGAAGAAGGCGCCGCACCGACTATGCGGG CGCTTCAGTCGCATCAGCATGAAGCTGCCCCGGATCCCGCTCCGGAGGCAGAAACTACCCAAAGTCGTAG TGGCCCACCACGACCTGGATAACACACTCAACTGCAGCTTCCTGGAGCCACCCTCAGGGCTGGAGCAGCC CTCACCATCCTGGTCCTCTCGGGCCTCCTTCTCCTCGTTTGACACCACTGATGAAGGCCCTGTGTACTGT GTACCCCATGAGGAGGCACCAGCGGAGAGCCGGGACCCCGAAGTCCCCACTGTCCCTGCCGAGGCGCCGG CGCCGTCCCCTGTGCCCTTGACCACGCCAGCCTCCGCCGAGGAGGCGATACCCCTCCCCGCGTCCTCCGA CAGCGAGCGGTCGGCGTCCAGCGTGGAGGGGCCCGGAGGGGCTCTGTACGCGCGCGTGGCCCGACGCGAG GCCCGGCCGGCCCGGGCCCGGGGCGAGATTGGGGGCCTGTCGCTGTCGCCATCGCCCGAGCGCAGGAAAC CGCCGCCACCTGACCCCGCCACCAAGCCTAAGGTGTCCTGGATCCACGGCAAGCACAGCGCCGCTGCAGC TGGCCGTGCGCCCTCACCACCGCCGCCAGGCTCCGAGGCCGCGCCCAGCCCCAGCAAGAGGAAACGGACG CCCAGCGACAAATCGGCGCATACGGTCGAACACGGCAGCCCCCGGACCCGCGACCCAACGCCGCGCCCCC CGGGGCTGCCCGAGGAGGCGACAGCCCTCGCTGCGCCCTCGCCGCCCAGGGCCCGAGCGCGCGCCGCGCC CCGGCCTCTTGGAGCCCACGGACGCCGGCGGTCCCCCGCGAAGCGCGCCGAGGCTGCCTCCATGTTGGCC GCTGACGTGCGCGGCAAGACTCGCAGCCTGGGCCGCGCCGAGGTGGCCCTGGGCGCGCAGGGCCCCAGGG AAAAGCCGGCGCCCCCACAGAAAGCCAAGCGCTCCGTGCCGCCAGCCTCGCCCGCCCGCGCGCCCCCAGC GACCGAAACCCCGGGGCCTGAGAAGGCGGCGACCGACTTGCCCGCGCCTGAGACCCCCCGGAAGAAGACC CCCATCCAGAAGCCGCCGCGCAAGAAGAGCCGGGAGGCGGCGGGCGAGCTGGGCAGGGCGGGCGCACCCA CCCTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA Protein Sequence (showhide) >RC212667 representing NM_182895 Red=Cloning site Green=Tags(s) MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQVPTCCAGWRQ QGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQ CTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRS CNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL GCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRC NAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS CHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRELSLGRKKAPHRLCG RFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYC VPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDSERSASSVEGPGGALYARVARRE ARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRT PSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLA ADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKT PIQKPPRKKSREAAGELGRAGAPTL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	AscI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_182895
ORF Size	2595 bp
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_182895.2, NP_878315.1
RefSeq Size	3508 bp
RefSeq ORF	2601 bp
Locus ID	91179
UniProt ID	Q96GP6
Protein Families	Druggable Genome
MW	91.8 kDa
Gene Summary	The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.