TOLLIP (NM_019009) Human Tagged ORF Clone
CAT#: RC200227
TOLLIP (Myc-DDK-tagged)-Human toll interacting protein (TOLLIP)
ORF Plasmid: tGFP
"NM_019009" in other vectors (6)
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CNY 2,400.00
CNY 4,465.00
Cited in 2 publications. |
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | IL-1RAcPIP |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC200227 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGACCACCGTCAGCACTCAGCGCGGGCCGGTGTACATCGGTGAGCTCCCGCAGGACTTCCTCCGCA TCACGCCCACACAGCAGCAGCGGCAGGTCCAGCTGGACGCCCAGGCGGCCCAGCAGCTGCAGTACGGAGG CGCAGTGGGCACCGTGGGCCGACTGAACATCACGGTGGTACAGGCAAAGTTGGCCAAGAATTACGGCATG ACCCGCATGGACCCCTACTGCCGACTGCGCCTGGGCTACGCGGTGTACGAGACGCCCACGGCACACAATG GCGCCAAGAATCCCCGCTGGAATAAGGTCATCCACTGCACGGTGCCCCCAGGCGTGGACTCTTTCTATCT CGAGATCTTCGATGAGAGAGCCTTCTCCATGGACGACCGCATTGCCTGGACCCACATCACCATCCCAGAG TCCCTGAGGCAGGGCAAGGTGGAGGACAAGTGGTACAGCCTGAGCGGGAGGCAGGGGGACGACAAGGAGG GCATGATCAACCTCGTCATGTCCTACGCGCTGCTTCCAGCTGCCATGGTGATGCCACCCCAGCCCGTGGT CCTGATGCCAACAGTGTACCAGCAGGGCGTTGGCTATGTGCCCATCACAGGGATGCCCGCTGTCTGTAGC CCCGGCATGGTGCCCGTGGCCCTGCCCCCGGCCGCCGTGAACGCCCAGCCCCGCTGTAGCGAGGAGGACC TGAAAGCCATCCAGGACATGTTCCCCAACATGGACCAGGAGGTGATCCGCTCCGTGCTGGAAGCCCAGCG AGGGAACAAGGATGCCGCCATCAACTCCCTGCTGCAGATGGGGGAGGAGCCA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC200227 protein sequence
Red=Cloning site Green=Tags(s) MATTVSTQRGPVYIGELPQDFLRITPTQQQRQVQLDAQAAQQLQYGGAVGTVGRLNITVVQAKLAKNYGM TRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPGVDSFYLEIFDERAFSMDDRIAWTHITIPE SLRQGKVEDKWYSLSGRQGDDKEGMINLVMSYALLPAAMVMPPQPVVLMPTVYQQGVGYVPITGMPAVCS PGMVPVALPPAAVNAQPRCSEEDLKAIQDMFPNMDQEVIRSVLEAQRGNKDAAINSLLQMGEEP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_019009 |
ORF Size | 822 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_019009.4 |
RefSeq Size | 3665 bp |
RefSeq ORF | 825 bp |
Locus ID | 54472 |
UniProt ID | Q9H0E2 |
Domains | C2, CUE |
Protein Families | Druggable Genome |
Protein Pathways | Toll-like receptor signaling pathway |
MW | 30.3 kDa |
Gene Summary | This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKK α and IKK β through the recruitment of TOLLIP
,null,
PLOS Pathogens
,PubMed ID 37566637
[TOLLIP]
|
Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy.
,null,
Autophagy
,PubMed ID 36343628
[TOLLIP]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC200227L1 | Lenti ORF clone of Human toll interacting protein (TOLLIP), Myc-DDK-tagged |
CNY 4,800.00 |
|
RC200227L2 | Lenti ORF clone of Human toll interacting protein (TOLLIP), mGFP tagged |
CNY 5,890.00 |
|
RC200227L3 | Lenti ORF clone of Human toll interacting protein (TOLLIP), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC200227L4 | Lenti ORF clone of Human toll interacting protein (TOLLIP), mGFP tagged |
CNY 4,800.00 |
|
RG200227 | TOLLIP (tGFP-tagged) - Human toll interacting protein (TOLLIP) |
CNY 4,000.00 |
|
SC320186 | TOLLIP (untagged)-Human toll interacting protein (TOLLIP) |
CNY 2,400.00 |