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FAIM2 (NM_012306) Human Tagged ORF Clone
CAT＃: RC200196
FAIM2 (Myc-DDK-tagged)-Human Fas apoptotic inhibitory molecule 2 (FAIM2)
ORF Plasmid: tGFP
"NM_012306" in other vectors (6)
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CNY 2,400.00
CNY 4,465.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | LFG; LFG2; NGP35; NMP35; TMBIM2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC200196 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCCAGGGAAAGCTCTCCGTGGCTAACAAGGCCCCTGGGACCGAGGGGCAGCAGCAGGTGCATGGCG AGAAGAAGGAGGCTCCAGCAGTGCCCTCAGCCCCACCCTCCTATGAGGAAGCCACCTCTGGGGAGGGGAT GAAGGCAGGGGCCTTCCCCCCAGCCCCCACAGCGGTGCCTCTCCACCCTAGCTGGGCCTATGTGGACCCC AGCAGCAGCTCCAGCTATGACAACGGTTTCCCCACCGGAGACCATGAGCTCTTCACCACTTTCAGCTGGG ATGACCAGAAAGTTCGTCGAGTCTTTGTCAGAAAGGTCTACACCATCCTGCTGATTCAGCTGCTGGTGAC CTTGGCTGTCGTGGCTCTCTTTACTTTCTGTGACCCTGTCAAGGACTATGTCCAGGCCAACCCAGGCTGG TACTGGGCATCCTATGCTGTGTTCTTTGCAACCTACCTGACCCTGGCTTGCTGTTCTGGACCCAGGAGGC ATTTCCCCTGGAACCTGATTCTCCTGACCGTCTTTACCCTGTCCATGGCCTACCTCACTGGGATGCTGTC CAGCTACTACAACACCACCTCCGTGCTGCTGTGCCTGGGCATCACGGCCCTTGTCTGCCTCTCAGTCACC GTCTTCAGCTTCCAGACCAAGTTCGACTTCACCTCCTGCCAGGGCGTGCTCTTCGTGCTTCTCATGACTC TTTTCTTCAGCGGACTCATCCTGGCCATCCTCCTACCCTTCCAATATGTGCCCTGGCTCCATGCAGTTTA TGCAGCACTGGGAGCGGGTGTATTTACATTGTTCCTGGCACTTGACACCCAGTTGCTGATGGGTAACCGA CGCCACTCGCTGAGCCCTGAGGAGTATATTTTTGGAGCCCTCAACATTTACCTAGACATCATCTATATCT TCACCTTCTTCCTGCAGCTTTTTGGCACTAACCGAGAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC200196 protein sequence
Red=Cloning site Green=Tags(s) MTQGKLSVANKAPGTEGQQQVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVPLHPSWAYVDP SSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGW YWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVT VFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNR RHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_012306 |
| ORF Size | 948 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_012306.4 |
| RefSeq Size | 4744 bp |
| RefSeq ORF | 951 bp |
| Locus ID | 23017 |
| UniProt ID | Q9BWQ8 |
| Domains | UPF0005 |
| Protein Families | Transmembrane |
| MW | 35.1 kDa |
| Gene Summary | Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Fas‐apoptotic inhibitory molecule 2 localizes to the lysosome and facilitates autophagosome‐lysosome fusion through the LC3 interaction region motif–dependent interaction with LC3
,Hong, C;Yeon, J;Yeo, B;Woo, H;An, H;Heo, W;Kim, K;Yu, S;,
FASEB j.
,PubMed ID 31914609
[FAIM2]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200196L1 | Lenti ORF clone of Human Fas apoptotic inhibitory molecule 2 (FAIM2), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC200196L2 | Lenti ORF clone of Human Fas apoptotic inhibitory molecule 2 (FAIM2), mGFP tagged |
CNY 5,890.00 |
|
| RC200196L3 | Lenti ORF clone of Human Fas apoptotic inhibitory molecule 2 (FAIM2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200196L4 | Lenti ORF clone of Human Fas apoptotic inhibitory molecule 2 (FAIM2), mGFP tagged |
CNY 5,890.00 |
|
| RG200196 | FAIM2 (tGFP-tagged) - Human Fas apoptotic inhibitory molecule 2 (FAIM2) |
CNY 4,000.00 |
|
| SC319390 | FAIM2 (untagged)-Human Fas apoptotic inhibitory molecule 2 (FAIM2) |
CNY 2,400.00 |
