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Il1r1 (NM_001123382) Mouse Tagged Lenti ORF Clone
CAT＃: MR227513L4
- LentiORF®
Lenti ORF clone of Il1r1 (mGFP-tagged) - Mouse interleukin 1 receptor, type I (Il1r1), transcript variant 2
"NM_001123382" in other vectors (4)
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CNY 7,600.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | CD121a; CD121b; IL-1R1; IL-iR; Il1r-1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR227513).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001123382 |
| ORF Size | 1719 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001123382.1, NP_001116854.1 |
| RefSeq Size | 4808 bp |
| RefSeq ORF | 1722 bp |
| Locus ID | 16177 |
| Gene Summary | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC219162 | Il1r1 (untagged) - Mouse interleukin 1 receptor, type I (Il1r1), transcript variant 2, (10ug) |
CNY 7,320.00 |
|
| MG227513 | Il1r1 (tGFP-tagged) - Mouse interleukin 1 receptor type I (Il1r1) transcript variant 2, (10ug) |
CNY 6,270.00 |
|
| MR227513 | Il1r1 (Myc-DDK-tagged) - Mouse interleukin 1 receptor, type I (Il1r1), transcript variant 2 |
CNY 5,700.00 |
|
| MR227513L3 | Lenti ORF clone of Il1r1 (Myc-DDK-tagged) - Mouse interleukin 1 receptor, type I (Il1r1), transcript variant 2 |
CNY 7,600.00 |
