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Nr4a1 (NM_010444) Mouse Tagged ORF Clone
CAT＃: MR209316
- TrueORF®
Nr4a1 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1)
ORF Plasmid: tGFP
"NM_010444" in other vectors (6)
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CNY 4,480.00
CNY 4,560.00
| Cited in 4 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | Gfrp; GFRP1; Hbr-1; Hbr1; Hmr; N10; NGFI-B; NGFIB; NP10; nur77; TIS1; TR3 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_010444 |
| ORF Size | 1806 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_010444.2 |
| RefSeq Size | 2534 bp |
| RefSeq ORF | 1806 bp |
| Locus ID | 15370 |
| UniProt ID | P12813 |
| MW | 64.7 kDa |
| Gene Summary | Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation (By similarity). Plays a role in the vascular response to injury (PubMed:22427340).[UniProtKB/Swiss-Prot Function] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1
,Li, W;Hang, S;Fang, Y;Bae, S;Zhang, Y;Wang, G;McCurry, M;Bae, M;Franzosa, E;Huttenhower, C;Yao, L;Devlin, A;Huh, J;,
bioRxiv
[NR4A1]
|
|
Consumption of a high fat diet promotes protein O-GlcNAcylation in mouse retina via NR4A1-dependent GFAT2 expression
,Dai, W;Dierschke, SK;Toro, AL;Dennis, MD;,
Biochim Biophys Acta Mol Basis Dis
,PubMed ID 30254013
[NR4A1]
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The effect of NR4A1 on APP metabolism and tau phosphorylation
,Zhao, L;Tang, Y;Tan, J;Wang, J;Chen, G;Zhu, B;,
Genes & Diseases
[NR4A1]
|
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NR4A1 Promotes PDGF-BB-Induced Cell Colony Formation in Soft Agar
,Eger, G;Papadopoulos, N;Lennartsson, J;Heldin, CH;,
PLoS ONE
,PubMed ID 25269081
[NR4A1]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC200008 | Nr4a1 (untagged) - Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1), (10ug) |
CNY 2,000.00 |
|
| MG209316 | Nr4a1 (tGFP-tagged) - Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1) |
CNY 5,040.00 |
|
| MR209316L1 | Lenti ORF clone of Nr4a1 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1) |
CNY 6,460.00 |
|
| MR209316L2 | Lenti ORF clone of Nr4a1 (mGFP-tagged) - Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1) |
CNY 6,880.00 |
|
| MR209316L3 | Lenti ORF clone of Nr4a1 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1) |
CNY 6,460.00 |
|
| MR209316L4 | Lenti ORF clone of Nr4a1 (mGFP-tagged) - Mouse nuclear receptor subfamily 4, group A, member 1 (Nr4a1) |
CNY 6,460.00 |
