ELK1 pSer383 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, IP, WB
Recommend Dilution	ELISA: 1:20000~1:40000. Western Blot: 1:500~1:1000. Immunohistochemistry: 1:50~1:200. Immunoprecipitation: 1:50~1:200.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Specificity	p-Elk1 (pSer383) antibody detects endogenous levels of p-Elk1 protein.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. State: Aff - Purified State: Liquid purified Ig
Concentration	1,0 mg/ml
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ELK1, ETS transcription factor
Database Link	Entrez Gene 2002 Human UniProt ID P19419
Background	Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar m otifs in DNA that share a centrally located 5'-GGAA-3' element.
Synonyms	Elk-1
Reference Data

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