Asialoglycoprotein Receptor 2 (ASGR2) (NM_080914) Human Mass Spec Standard

CAT#: PH317541

ASGR2 MS Standard C13 and N15-labeled recombinant protein (NP_550436)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ASGR2 MS Standard C13 and N15-labeled recombinant protein (NP_550436)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217541
Predicted MW 32.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_550436
RefSeq Size 1202
RefSeq ORF 876
Synonyms ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2
Locus ID 433
Cytogenetics 17p13.1
Summary This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Protein Families Druggable Genome, Transmembrane
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