ILKAP (NM_030768) Human Mass Spec Standard

Specifications

Product Data
Description	ILKAP MS Standard C13 and N15-labeled recombinant protein (NP_110395)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201456
Predicted MW	42.9 kDa
Protein Sequence	Sequence Link (showhide) >RC201456 protein sequence Red=Cloning site Green=Tags(s) MDLFGDLPEPERSPRPAAGKEAQKGPLLFDDLPPASSTDSGSGGPLLFDDLPPASSGDSGSLATSISQMV KTEGKGAKRKTSEEEKNGSEELVEKKVCKASSVIFGLKGYVAERKGEREEMQDAHVILNDITEECRPPSS LITRVSYFAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQK PAWKDGSTATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGNVRD GRVLGVLEVSRSIGDGQYKRCGVTSVPDIRRCQLTPNDRFILLACDGLFKVFTPEEAVNFILSCLEDEKI QTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVVRIGH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_110395
RefSeq Size	1480
RefSeq ORF	1176
Synonyms	ILKAP2; ILKAP3; PP2C-DELTA; PP2CD; PPM1O
Locus ID	80895
Cytogenetics	2q37.3
Summary	The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Phosphatase

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