RAD54 (RAD54L) Human Gene Knockout Kit (CRISPR)

CAT#: KN220046BN

RAD54L - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

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CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit polyclonal anti-RAD54 antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


RAD54L (Myc-DDK-tagged)-Human RAD54-like (S. cerevisiae) (RAD54L), transcript variant 1
    • 10 ug

CNY 5,472.00
CNY 5,800.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol RAD54
Locus ID 8438
Kit Components

KN220046G1, RAD54 gRNA vector 1 in pCas-Guide CRISPR vector

KN220046G2, RAD54 gRNA vector 2 in pCas-Guide CRISPR vector

KN220046BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001142548, NM_003579, NM_001370766
Synonyms hHR54; HR54; hRAD54; RAD54A
Summary The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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