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Over-expression Lysates

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qPCR Primer Pairs

CytoSections

siRNA Oligo Duplexes

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3' UTR Clones

qPCR Template Standards

Mass Spec Standards

Mutant ORF Clones

ELISA Kits

MicroRNA Expression Plasmids

Native Proteins

Mutant Proteins

Lentiviral Particles

cDNA Clone Sets

Mutant CytoSections

Human

Mouse

Rat

Virus

SARS-CoV-2

Cynomolgus

Bovine

Monkey

Escherichia coli

Rabbit

Rhesus

Chicken

HCoV-HKU1

Pig

Canine

Equine

Coronavirus IBV

Blomia tropicalis

HECV-4408

HCoV-OC43

2019-nCoV

Dermatophagoides pteronyssinus

HCoV-229E

Hamster

HCoV-NL63

Orf Virus

Sheep

Staphylococcus aureus

Streptococcus Pyogenes

Porcine

Hepatitis B Virus

Saccharomyces cerevisiae

Cavia porcellus

Dermatophagoides farinae

HIV

Streptococcus sp.

Alternaria alternata

B.subtilis

Betula pendula

Carassiusauratus

Chlorocebus aethiops

D. aromatica

Drosophila melanogaster

E.coli

Enterobacteria phage T4

Escherichia phage T7

GFP

HIV-1

Helicobacter pylori

Human herpesvirus

Human papillomavirus

Humon

Humulus japonicus

Klebsiella pneumoniae

Lachnospiraceae bacterium ND2006

Lepidoglyphus destructor

Leptotrichia wadei

Macaca fascicularis

Marmoset

Mucor hiemalis

Mus musculus

Mycoplasma

Proteobacteria

S. hygroscopicus

SIV

Serratia marcescens

Staphylococcus aureus subsp.

Streptococcus

Streptomyces avidinii

Streptomyces plicatus

T. fusca

Tobacco etch virus

Vaccinia virus

Vacciniavirus

Varicella Zoster Virus

Vibrio cholerae

viral

BRCA1

BTK

GLUCOKINASE

MENIN

BRCA2

MLH1

TUBERIN

MSH2

IFNG

P53

RET

FGFR1

PDE9A

NOTCH3

BDNF

DISC1

VEGFA

CREM

NF2

NRG1

ALPHA 1 ANTITRYPSIN

CONSTITUTIVE ANDROSTANE RECEPTOR

MORTALITY FACTOR 4 LIKE 2

NDRG2

BIN1

UBE2D3

CTNND1

G PROTEIN ALPHA S

WILMS TUMOR PROTEIN

IL10

IRF5

DYSTROBREVIN ALPHA

EGFR

EMA

MU OPIOID RECEPTOR

MSH6

NCALD

DYSTROPHIN

ST3GAL3

CACNA1G

RIBONUCLEASE INHIBITOR

PLAGL1

FGF1

IL32

HMGA1

TGIF

TPM1

CD46

FHL1

LKB1

PQBP1

SYTL2

BETA CATENIN

SYNTABULIN

ASPARTATE BETA HYDROXYLASE

SSH3BP1

UBE2V1

APC11

OSBPL9

PCBP2

NAT1

CAMK2B

MEIS2

RUNX1T1

MYOSIN

TCF7L2

FGFR2

HFE

HNF 4 ALPHA

MAX

MTH1

PML PROTEIN

UTY

ATAXIN 3

CPNE1

FH

IKZF3

MBNL1

RGS3

ALKALINE PHOSPHATASE

CD1E

CD59

GM CSF RECEPTOR ALPHA

PRKAR1B

TAU

PPP2R2B

AURORA A

IKAROS

RAD17

ZFYVE27

CACNA1C

CAMKK2

CD44

CHRM2

GPR56

HNRNP F

NEK6

OGG1

ESTROGEN RELATED RECEPTOR GAMMA

UBE2I

Human

WB

IHC

HEK293T

HEK293

E. coli

Sf9

Insect

CHO

Pichia

Baculovirus

Pichia pastoris

Sf9 insect

human serum

H. vulgare

Human

Other

Plasmids

Particles

Myc-DDK

C-Myc/DDK

Tag Free

TurboGFP

mGFP

C-MYC/DDK

N-His

C-His

N-GST and C-His

C-Fc

C-DDK

C-6His

N-GST and C-HIS

N-GST

C-DDK/His

DDK-His

His-tag

C-Fc&His

N-His-ABP (Albumin-Binding Protein)

C-HIS

C-Human Fc

C-mFc

N-His&C-His

C-6His-Avi

N-6His

C-Mouse Fc and 6×His

His-Tag

N-T7&C-His

N-Trx&His

C-8His

C-Mouse Fc

N-His-Trx

C-Fc-Avi

C-hFc

C-6×His

C-Avi-6His

C-Human Fc and 6×His

N-GST, C-His

C-10His

N-Fc

N-His&SUMO

N-GST&His

C-Avi&6His

Tag-free

C- 6×His

hIgG-Tag

C-Fc&AVI

N-Avi

N-HIS

N-His PDCD1(Pro21-Val170)

N-Mouse Fc and C-6×His

C-6xHis

N-His&C-Fc

N-His&T7

N-His-GST

N-His/DDK

N-MARI

N-Trx

C-Fc/His

C-hFc&His

N-8His

hIgG-His-Tag

C-Flag

C-HUMAN

C-Myc-DDK

N-6His-Avi

N-DDK

N-His&Flag

N-His-PDCD1(Pro21-Val170)

N-Human Fc

N-mFc

N-terminal His

N-terminal His-PDCD1(Pro21-Val170) tag

C-6xHis/AVI

C-AVI

C-AVI&His

C-AVI-PLUS

C-Avi

C-Avi-10His

C-Avi-His

C-DDK-His

C-DDK/10xHis

C-DDK/6xHis

C-FC

C-FC-6HIS&C-FC-Flag

C-Fc-Flag&C-Fc-6His

C-Flag,C-6His

C-GST

C-HIS/C

C-HIS/DDK

C-His&AVI

C-His&Flag

C-His&HA&AVI

C-His/DDK

C-Human Fc, Avi

C-Human Fc-Avi

C-hIgG1 Fc

C-hIgG2 Fc

C-hIgG4 Fc

C-hIgG4P Fc

C-mFC

C-mIgG2a Fc

C-mIgG2aFc

C-terminal DDK

C-terminal His

N-10His-Flag

N-6His-FLAG

N-6His-Flag

N-8His&N-FLAG

N-8His-Flag

N-AVI

N-AVI&His

N-Avi&6His

N-DDK/His

N-FC

N-FLAG

N-FUSION

N-Fc-FLAG

N-Flag&C-His

N-Flag&His

N-GFP

N-GST(CKM) and N-His(CKB)

N-Mouse Fc

N-T7

N-TRX

N-TRXA

N-Trx-His

N-hFc

No

Tag free

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pRS

pGFP-C-shLenti

EF1a-GFP-P2A-Puro

pCMV6-XL5

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL4

pCMV6-AC

pCMVMIR

pGFP-V-RS

RFP-BSD

Luciferase-Puro

mBFP-Neo

GFP-puro

pRFP-C-RS

pCMV6-XL6

PCMV6-Neo

pCMV6-AC-Myc-DDK

pCMV6-XL5-DDK-His

pCMV6-AN-Myc-DDK

pRMT-tGFP, Promoter-less GFP Reporter Vector

pCMV6-Entry2

None

TurboGFP

GFP

RFP

PE

No

Yes

Sandwich

LentiORF

TrueORF

TrueClone

MVPro

TrueORF Gold, TrueORF

SDS PAGE

Druggable Genome

Transmembrane

WB

Transcription Factors

Secreted Protein

Protein Kinase

Protease

ES Cell Differentiation/IPS

Stem cell - Pluripotency

GPCR

Phosphatase

Ion Channels: Other

Adult stem cells

Nuclear Hormone Receptor

Embryonic stem cells

Ion Channels: Potassium

Cancer stem cells

P450

Induced pluripotent stem cells

Ion Channels: Cys-loop Receptors

Stem cell relevant signaling - JAK/STAT signaling pathway

Ion Channels: Transient receptor potential

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Ion Channels: Glutamate Receptors

Ion Channels: Calcium

Ion Channels: Sodium

Ion Channels: ATP Receptors

Ion Channels: Cyclic nucleotide gated

ELISA

SDS-PAGE

Bioactivity

10 mM Tris-HCl

the solution can be further dialyzed against PBS (phosphate buffered saline

Flow Cyt

2 mM dithiothreitol

ELISA.
Western Blot.

e.g. Dulbecco's PBS).

Enzyme Activity

both dissolved in 9.5 M urea buffer (see above). Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

pH 7.4). For immunization purposes

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

pH 7.4).
For immunization purposes

pH 7.4).
For immunization purposes

Western Blot.

0.1% (w/v) insulin

10mM Tris-HCl

1mM DTT

2 mM dithiothreitol

2mM EDTA.
2. Add 4ug of recombinant thioredoxin into reaction cocktail and mix immediately.
3. Incubate at 25°C for 20 minutes.
4. Record the increase in A650nm for 15 minutes

2mM dithiothreitol

63mM sodium phosphate

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: After vimentin is dissolved in 9.5M Urea buffer (see above)

Can be used as standard in a Sandwich ELISA.

FACS

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: after desmin is dissolved in 9.5 M urea buffer (see above)

Protocol: Activity Assay
1. Prepare a 1 ml reaction cocktail into a suitable container: The final concentrations are 5mM Tris

Recombinant E. coli derived Human Sonic HedgeHog is a 20.0 kDa protein consisting of 176 amino acid residues

Secreted

both dissolved in 9.5 M urea buffer (see above).
Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

e.g. Dulbeccos PBS).

e.g.Dulbecco's PBS).

including an N-terminal Ile-Val-Ile sequence substituted for the natural occurring chemically modified Cys residue.

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M Urea and then to low salt condition (50mM NaCl

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M urea and then to low salt condition (50 mM NaCl

the solution can be further dialyzed against PBS (Phosphate Buffered Saline

ELISA.
Suitable for use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.

ELISA.
Western Blot.

ELISA.
Western blotting.

ELISA.

Positive control for Western blot analysis

Positive control for Western blot analysis.
Standard for ELISA.

Adermann K. Role of the prosequence of guanylin. Protein Sci. 1999 Sep; 8(9): 1850-9.
4. Lauber T

Cell culture and/or animal studies.
ELISA.
Western Blot.

Cohen MB. Proguanylin secretion and the role of negative-feedback inhibition in a villous epithelial cell line. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3): G695-702.
3. Schulz A

ELISA.
Western blotting.

For use as a Control or Standard in Indirect trapping ELISA for quantitation of antigen in serum using a standard curve

For use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.

Forssmann WG

Hawkins JA

Hidaka Y

Marx UC

Marx UC. Native and recombinant proguanylin feature identical biophysical properties and are monomeric in solution. Biochemistry. 2002 Dec 10; 41(49): 14602-12.
2. Rudolph JA

Marx UC. Solution structure of human proguanylin: the role of a hormone prosequence. J Biol Chem. 2003 Jun 27; 278(26): 24118-24. Epub 2003 Apr 21.

Neudecker P

Nourse A

Rosch P

Schulz A

Shimonishi Y

Specific methodologies have not been tested using this product.

Western Blot.
Protocol: 1. Lauber T

Western Blotting.

for immunoprecipitation and for Wwestern blotting.

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Neuroactive ligand-receptor interaction

Endocytosis

Chemokine signaling pathway

Neurotrophin signaling pathway

Insulin signaling pathway

Calcium signaling pathway

Ubiquitin mediated proteolysis

Wnt signaling pathway

Jak-STAT signaling pathway

Huntington's disease

Purine metabolism

Natural killer cell mediated cytotoxicity

Alzheimer's disease

Colorectal cancer

Axon guidance

Olfactory transduction

Tight junction

Cell cycle

T cell receptor signaling pathway

Prostate cancer

Progesterone-mediated oocyte maturation

Leukocyte transendothelial migration

Cell adhesion molecules (CAMs)

ErbB signaling pathway

Pancreatic cancer

Oocyte meiosis

Toll-like receptor signaling pathway

Apoptosis

Melanoma

GnRH signaling pathway

Adherens junction

Lysosome

Vascular smooth muscle contraction

Hematopoietic cell lineage

Melanogenesis

B cell receptor signaling pathway

Fc gamma R-mediated phagocytosis

Fc epsilon RI signaling pathway

Chronic myeloid leukemia

p53 signaling pathway

Endometrial cancer

Dilated cardiomyopathy

Glioma

Small cell lung cancer

VEGF signaling pathway

Renal cell carcinoma

Spliceosome

Gap junction

Hypertrophic cardiomyopathy (HCM)

Parkinson's disease

Systemic lupus erythematosus

Pyrimidine metabolism

Acute myeloid leukemia

Non-small cell lung cancer

Oxidative phosphorylation

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Long-term potentiation

TGF-beta signaling pathway

mTOR signaling pathway

Long-term depression

Adipocytokine signaling pathway

Glycolysis / Gluconeogenesis

PPAR signaling pathway

Antigen processing and presentation

Bladder cancer

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

Phosphatidylinositol signaling system

Type II diabetes mellitus

Viral myocarditis

Epithelial cell signaling in Helicobacter pylori infection

Complement and coagulation cascades

Thyroid cancer

Amyotrophic lateral sclerosis (ALS)

ECM-receptor interaction

Cardiac muscle contraction

Pathogenic Escherichia coli infection

Ribosome

Glycerophospholipid metabolism

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Amino sugar and nucleotide sugar metabolism

Cytosolic DNA-sensing pathway

Basal cell carcinoma

Vibrio cholerae infection

Inositol phosphate metabolism

Starch and sucrose metabolism

Arginine and proline metabolism

Primary immunodeficiency

Hedgehog signaling pathway

Mismatch repair

Valine

Retinol metabolism

Glutathione metabolism

Drug metabolism - other enzymes

RNA degradation

Autoimmune thyroid disease

Notch signaling pathway

Arachidonic acid metabolism

Tyrosine metabolism

Type I diabetes mellitus

leucine and isoleucine degradation

Pyruvate metabolism

Nucleotide excision repair

Fatty acid metabolism

Glycerolipid metabolism

Galactose metabolism

Proteasome

Homologous recombination

Lysine degradation

Taste transduction

Tryptophan metabolism

Prion diseases

Sphingolipid metabolism

Maturity onset diabetes of the young

Cysteine and methionine metabolism

Graft-versus-host disease

Base excision repair

Fructose and mannose metabolism

N-Glycan biosynthesis

Dorso-ventral axis formation

Citrate cycle (TCA cycle)

Alanine

Allograft rejection

aspartate and glutamate metabolism

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

SNARE interactions in vesicular transport

Propanoate metabolism

Regulation of autophagy

DNA replication

Butanoate metabolism

Aminoacyl-tRNA biosynthesis

Pentose phosphate pathway

Ether lipid metabolism

Nitrogen metabolism

Histidine metabolism

Glycine

serine and threonine metabolism

ABC transporters

Glycosphingolipid biosynthesis - lacto and neolacto series

Selenoamino acid metabolism

Basal transcription factors

Asthma

Linoleic acid metabolism

Glycosaminoglycan degradation

Phenylalanine metabolism

RNA polymerase

Nicotinate and nicotinamide metabolism

beta-Alanine metabolism

O-Glycan biosynthesis

Pentose and glucuronate interconversions

Pantothenate and CoA biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Riboflavin metabolism

Ascorbate and aldarate metabolism

One carbon pool by folate

Sulfur metabolism

Primary bile acid biosynthesis

Renin-angiotensin system

Biosynthesis of unsaturated fatty acids

Other glycan degradation

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Terpenoid backbone biosynthesis

Glyoxylate and dicarboxylate metabolism

alpha-Linolenic acid metabolism

Steroid biosynthesis

Glycosphingolipid biosynthesis - globo series

Chondroitin sulfate biosynthesis

Non-homologous end-joining

Limonene and pinene degradation

Circadian rhythm - mammal

Glycosphingolipid biosynthesis - ganglio series

C21-Steroid hormone metabolism

leucine and isoleucine biosynthesis

Taurine and hypotaurine metabolism

Folate biosynthesis

Cyanoamino acid metabolism

Thiamine metabolism

Protein export

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Lysine biosynthesis

Lipoic acid metabolism

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

O-Mannosyl glycan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Human

E. coli

Human 293

Plasma

Placenta

Baculovirus

Erythrocytes

Neutrophils

P.Pichia

293F

Brain

CHO Stable

Carcinoma

HEK293

Leukocytes

Mammalian

Pancreas

Pichia pastoris

Pituitary

Synthetic

Urine

96-well plate

Neomycin

Puromycin

None

1

2

3

Yes

In Stock